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《Hereditas》 2008-01
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piRNA:A novel member of small RNA family

GUO Yan-He, LIU Li, CAI Rong, QIAN Cheng Xin Yuan Institute of Medicine and Biotechnology, College of Life Science, Zhejiang Sci-Tech University, Hangzhou 310018, China  
It has been demonstrated that microRNA (miRNA) and small interfering RNA(siRNA) play an important role in the basically physiological regulation of eukaryotic organisms. With the intensive study on siRNA and miRNA, scientists recently have discovered that there exists a novel type of small RNA named as piRNA in the mammalian testes, which is essential for physiological modulation of spermiogenesis and different from miRNA or siRNA in functions, gene distribu-tions and characteristics. It is well believed that the more intensive research on piRNA will throw light on the delicate mechanisms of gene expression modulation for eukaryotic species.
【Fund】: 国家重点基础研究发展规划(973计划)项目(编号:2004CB518804);; 国家高技术研究发展计划项目(863计划)(编号:2006AA02Z126 2007AA02Z134);; 浙江省社会发展重点项目(编号:2006C23006)资助~~
【CateGory Index】: Q522
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