Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Sports Medicine》 2004-01
Add to Favorite Get Latest Update

The Influences of Immune Suspression by Oral Administration of Type Ⅱ Collagen on Rat Rheumatic Osteoarthritis and Traumatic Osteoarthritis

Sun Jie and Yu Changlong (correspondent author) Institute of Sports Medicine, Peking University,Beijing 100083, China  
Purpose: To study the influences of immune suspression by oral administration of type Ⅱ collagen on the pathogenesis of collagen induced arthritis(CIA) and traumatic oseoarthritis(OA) in rats; Methods: Rat knee traumatic osteoarthritis model made by excision of medial collateral ligament and medial meniscetomy and CIA model were applied for the observation of the changes on hisological and histochemical staining and the inhibition of T cells after oral administration of type Ⅱ collagen. Results: In OA, although the T cells were suspressed by oral administration of type Ⅱ collagen, however, the the pathogenesis was not hindered comparing with RA. It indicated that for OA, machanical factor is more important than the immunological factor, oral administration of type Ⅱ collagen has little effect on decreasing the speed of development of OA. It is not adequate to take the remedy of oral administation of type Ⅱ collagen for the treatment of OA.
【CateGory Index】: R593.22;R684.3
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 1 Hits
1 LU Xue-qin,XU Shi-ying* (School of Food Science and Technology, Jiangnan University, Wuxi 214122, China);Effects of Chick Sternal Cartilage and Glucosamine Sulfate on Rheumatoid Arthritis in Sprague-Dawley Rats[J];Food Science;2008-04
【Citations】
Chinese Journal Full-text Database 1 Hits
1 Zhao Jingyuan ; Yu Changlong ;Ao Yingfang , et al( Institute of Sports Medicine, Beijing Medical University) Using the method of exercising the medial collateral ligament and extirpating the medial meniscus , an ani - mal model of early osteoarthritis (;The Study of Pathogenesis of Early Osteoarthristis in Rabbits[J];CHINESE JOURANAL OF SPORTS MEDICINE;1998-03
【Co-citations】
Chinese Journal Full-text Database 7 Hits
1 ZHANG Xiao-Ling, Yu Chang-Long △ (Institute of Sports Medicine, Peking University Third Hospital,Beijing 100083,China);Current status and prospects of gene therapy approaches for osteoarthritis[J];Journal of Beijing Medical University;2002-05
2 ZHANG Mei~1, LI Ping~1, WANG Jian~1, ZHAI Zhi-ming~1, HU Wen~1, CHEN Zhao-hui~2 (1. Anhui Prinvince Hospital, 2.Anhui College of Traditional Chinese Medicine, Heifei 230001, China);Establishment of Three Models on Chondrocyte Apoptosis[J];Shanghai Laboratory Animal Science;2004-01
3 Su Hai li, Qiu Ping,Tang Jin song,Wang Yong jiang,Li Guo pu Su Hai li, Qiu Ping,Tang Jin song,Wang Yong jiang,Li Guo pu,Department of Rehabilitation Medicine, Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China;Changs of loading on knee joint for articular cartilage[J];Chinese Journal of Clinical Rehabilitation;2005-06
4 Dai GG,Liu B,Luo XB,Peng XM 1Sichuan Orthopedic Hospital,Chengdu 610041,Sichuan Province,China; 2Electron Microscope Laboratory of Forensic Medicine,West China Center of Medical Science,Sichuan University,Chengdu 610041,Sichuan Province,China;Surface of normal rabbit knee articular cartilage:A scanning electron microscope study[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2007-32
5 Yu Shibing~1, Zhao Xia~2, Fu Xin~1, Wu Fenglan~2, Zhang Jiying~1, Mao Zebin~3, Yu Changlong~1 1 Institute of Sports Medicine, Peking University Third Hospital, Beijing,China 100083 2 The Department of Pharmacy, Peking University School of Pharmaceutical Science, Beijing,China 100083 3 The Department of Biochemistry and Molecular Biology, Peking University School of Basic Medical Sciences, Beijing,China 100083;Chitosan-based Gene Therapy for Experimental Osteoarthritis[J];Chinese Journal of Sports Medicine;2006-02
6 Chen Lianxu, Yu Changlong, Wang Haijun, Lin Lin, Wei Xuelei, Fu Xin, Zhzng Jiying Institute of Sports Medicine, Third Hospital of Peking University, Beijing,China 100083;The Expression of NF-κBp65 in Traumatic Osteoarthritis[J];Chinese Journal of Sports Medicine;2007-04
7 ZOU Ben-guo,HUANG Chen,REN Xu-rong,et al.Department of Orthopaedic Oncology,Yantaishan Hospital,Yantai,Shandong 264001,China;The changes of bone mineral density and bone structure in osteoporosis and osteoar thritis rats[J];Chinese Journal of Modern Drug Application;2008-05
China Proceedings of conference Full-text Database 1 Hits
1 Yu Changlong;Devlopment of sports Traumatology:A Fundamental Account[A];[C];2007
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Guan Jing Ye Ping Wu Jimin (Institute of Medical Equipment, Academy of Military Medical Sciences, Tianjin 300161);The determination of hydroxyproline in collagen sponge[J];AMINO ACIDS & BIOTIC RESOURCES;2000-01
2 TAO Yan, WANG Zao (College of Food Science, Shanghai Fisheries University, Shanghai 200090, China);Evaluation of Nutritive Value of Creamy Fish Protein[J];Amino Acids & Biotic Resources;2005-01
3 Lu ping;Zhang Linsheng;Cao Rang(Central Laboratory,Northwestern Agricul tural University,Yanglin,shanxi 712100,PRC);Studies on the Determination Method of Hydroxyproline in Animal Adipose Tissue[J];;1994-02
4 Liu Zhiguang and Ma Haiyan(Department of Pathology, The Fourth Military Medical University);Research and Application of a Fast Method to Determinate Collagen Specific Amno Acids[J];;1994-03
5 ZHANG Zhi-sheng~(1,2),LIU An-jun~1,LIU Yuan~2,JIAN Jing-ying~2 (1.College of Food Eengineering & Biotechnology,Tianjin University of Science & Technology,Tianjin 300122,China;2.College of Animal Science and Technology,Agricultural University of Hebei,Baoding 071001,China);Suppression of sheep type II collagen by oral administration on KM mice with adjuvant-induced arthritis[J];Journal of Agricultural University of Hebei;2006-05
6 LENG Nan,ZHU Ping,WANG Yan Hong,HAN Jie,WU Zhen Biao,ZHANG Hui Qin, XIE Hui,FAN Chun Mei Department of Clinical Immunology,Xijing Hospital,Fourth Military Medical University, Xi'an 710033,China;Suppression of adjuvant arthritis in rats by oral administration of collagen[J];Journal of The Fourth Military Medical University;2001-08
7 WANG Xiao-yan 1,CAI Ji-ye 1*,LIANG Zhi-hong 2,ZHAO Tao 1 (1 Department of Chemistry,Jinan University,Guangzhou Guangdong 510632; 2 Center of Experiment and Technology,Jinan University,Guangzhou Guangdong 510632,China);Morphological studies ofⅠtype collagen fibril from different species by AFM[J];Journal of Chinese Electron Microscopy Society;2003-02
8 LIU Yi~* and QIAN He (School of Food Science and Technology, Southern Yangzte Univeristy, Wuxi 214036);Spectrophotometric quantitative determina- tion of glycosaminoglycans in sea cucumber tissues with 1,9-dimethylmethylene blue[J];Analytical Laboratory;2005-06
9 CAO Zheng-guo,LI Cheng-zhang (College & Hospital of Stomatology,WuHan University,WuH an 430079,China);The common protein cross-linking methods and their effects on collagen[J];Foreign Medical Sciences Biomedical Engineering;2001-04
10 ZHAO Cang-bi, HUANG Yu-dong, LI Yan-hui(Dept. of Applied Chemistry, Harbin Institute of Technology, Harbin 150001,China, );Extraction of collagen from cattle tendons[J];Journal of Harbin Institute of Technology;2004-04
【Secondary References】
Chinese Journal Full-text Database 4 Hits
1 SHA Li-na1,LI Zhen-fei1,HAN Tian-xiang2(1.Collage of Food Science and Engineering,Inner Mongolia Agricultural University,Huhhot 010018,China; 2.Collage of Food Science and Engineering,ocean university of Guangdong,Zhanjiang 524088,China);LMPROVED PROCESS FOR DEGREASING AND DECALCIFICATION OF COLLAGEN TYPE Ⅱ FROM SHEEP CARTILAGE[J];Journal of Inner Mongolia Agricultural University(Natural Science Edition);2012-04
2 CHEN Jie1,YASUNOBU Masuda2,MIKA Usuda2,MAMORU Kimura2,XU Wen-bin1,ZHENG Chao-peng1,HONG Yi-lan1,REN Xiao-jing1,XI Yin-ci1,(1.College of Food Science and Technology,Shanghai Ocean University,Shanghai 201306,China;2.Japan Kewpie Corporation,Tokyo 1500002,Japan);Therapeutic Effect of Oral Administration of Hyaluronic Acid on Adjuvant Arthritis in Mice[J];Food Science;2012-23
3 LI Li-xiao1,2,XIA Yan-bin1,2,*(1.College of Food Science and Technology,Hunan Agricultural University,Changsha 410128,China;2.National R&D Branch Center for Vegetable Processing,Changsha 410128,China);Optimization of Enzymatic Pretreatment for Chondroitin Sulfate from Bovine Nose Cartilage[J];Food Science;2012-24
4 LI Zhen-fei, SHA Li-na * (College of Food Science and Engineering, Inner Mongolia Agricultural University, Huhhot 010018);Isolation, purification and identification of type Ⅱ collagen from sheep cartilage[J];Food Science and Technology;2013-03
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 Yu Changlong;Qu Mianyu;Tian Xiaoming Institute of Sports Medicine, Beijing Medical College;AN EXPERIMENTAL PATHOLOGICAL STUDY OF ENTHBSIOPATHY OF RABBIT'S ACHILLES TENDON[J];Chinese Journal of Sports Medicine;1983-03
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved