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《Chinese Journal of Sports Medicine》 2010-01
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A Experimental Pathological Study of Different Frequency Extracorporeal Shock Wave Induced Tibia Osteogenesis in Rabbits

Zhang Jiying,Hou Yu,Xue Tao,Duan Xiaoning,Fu Xin,Tian Ming,Yu Changlong Institute of Sports Medicine,Peking University Third Hospital,Beijing,China 100191  
Objective To investigate the osteogenesis capability of different frequency extracorporeal shock wave.Methods 39 rabbits received different frequency extracorporeal shock wave at the middle potion of tibia for 3 or 7 dayst,hese rabbits were then sac rificed and the tibia bones were collected to process for HE and toluidine blue stainingt,he pathological changes were observed under the light microscope.Results After different frequency extracorporeal shock wave treatmentt,he typical periosteal reaction were observed,external periosteum bleeded and thickened but there was no reaction at internal periosteum,marrow cavity opened and fibrosedt,he osteoblast-liking cell proliferated,however,no cartilage cells were observed;The rabbits received 7 days shock wave treatment showed more severe reaction than those for 3 days.The shock wave at lower frequency showed more severe reaction than higher frequency.Conclusion shock wave induced osteogenesis through the periosteal reaction of external periosteum;the osteogenesis capability of different frequency extracorporeal shock wave were affected by the frequency.Higher frequency of shock wave was not the ideal way to promote osteogenesis.
【Fund】: 国家体育总局课题(异位骨化的基因治疗)
【CateGory Index】: R687.3
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