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《Acta Universitatis Medicinalis Anhui》 1987-01
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Evaluation of Therapeutic Effects of TAD Chemotherapy Regimen of Acute Nonlymphocytic Leukemia

Cai Xuejie  
TAD(thioguanine,cytosine arabinoside daunorubicin)regi- men was used in treatment of 12 cases aged from 17-47 of untreated ANLL.The total effective rate was 66.7% the complete remisson(C R)rate was 41.7%.5 cases got CR in 26-66 days,mean 53 days,bet- ter than other authors,but the CR duration(2~9 months,mean 6.2 months)was shorter than others.The main side effect of TAD regimen on heart was slight.The value of decrease in the percentage of leukemic blast cells in bone marrow,after the second course rather than the first course of TAD induction chemotherapy in the prediction of response to subsequent therapy was evaluted,4 out of 5 patients of decrease in percentage of leukemic blast cells to less than 20% of the total number of the nucler cells(in the bone marrow)achieved complete remission.
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