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Effect on learning and memory and antioxidationof total lactones ginkgo in presenium

Li Guifang , Dong Liuyi, Gao Shan et al(Dept of Pharmacology, Anhui Medical University, Hefei 230032)  
Objective To study the effect on learning and memory and antioxidation of total lactones ginkgo (TLG) in natural presenium Methods The model of natural aging mouse was used. Learning and memory of mice was determined by step down test. The content of malondialdehyde(MDA) and the activity of superoxide dismutase(SOD) was detected using blood and cerebro tissues of mice Results TLG significantly re duced times of errors while the mice were trained and tested in step down TLG raised the activity of SOD in blood and cerebro tissues of mice and decreased the content of MDA in cerebro tissues Conclusion TLG possesses significant eff ect of promoting learning and memory It may enhance the ability of antioxidation of body
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