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Application and progress of molecularly imprinted technique in analytical chemistry

LI Chun-xiang,WANG Ling-ling,XU Wan-zhen,LI Song-tian,DENG Yue-hua,YAN Yong-sheng*(School of Chemistry and Chemical Engineering,Jiangsu University,Zhenjiang 212013,China)  
Molecular imprinted technique has the characteristics of specificity and high selectivity.Its key is the screening of functional monomer and template molecule,polymerization and the elution of template molecule.The preparation methods of molecular imprinted polymers include embedding method,affinity imprinting method,freeze-drying method and surface imprinted method.Molecular imprinting technique is widely applied to analytical chemistry such as chromatographic analysis,environmental trace analysis,membrane separation,chiral separation,and the separation/ enrichment of metal ions,sample pretreatment,sensor and the screening of effective components in chinese drugs.The research direction for molecular imprinted technique in future includes understanding the mechanism of molecular imprinting and identification from molecular level,exploring new synthetic method,realizing the transfer of molecular imprinting technique from organic phase to water phase,from nonpolar solvent environment to polar solvent environment and extending its application field.
【Fund】: 江苏省研究生培养创新工程(CX07B-176z);; 科技部创新基金项目(05C26213100474)
【CateGory Index】: O652
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【Co-citations】
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