Saponin Constituents from Fruits of Panax ginseng
TAO Li;LI Ke-ke;LI Dong-xia;GONG Xiao-jie;Medical College of Dalian University;
Objective: To study the saponin constituents of in the fruits of Panax ginseng C. A. Meyer. Methods:The chemical constituents were isolated and purified by various chromatographic methods including macroporous resin,MCI gel, silica gel columns and semi-preparative HPLC, and their structures were identified by NMR and MS data analysis. Results: Twenty-two compounds were isolated and identified as ginsenoside F2(1),vina-ginsenoside R8(2),pseudoginsenoside Rc1(3),ginsenoside Re(4),notoginsenoside R2(5),ginsenoside F5(6),ginsenoside F3(7),ginsenoside Ia(8),chikusetsusaponin LM1(9),20(S)-ginsenoside Rg2(10),ginsenoside Rc(11),ginsenoside F1(12),ginsenoside Rd(13),ginsenoside Rb2(14),ginsenoside Rb1(15),ginsenoside Rh6(16),ginsenoside Rh4(17),ginsenoside Rh5(18),gypenoside XⅦ(19),gypenoside IX(20),notoginsenoside Fe(21) and quinquenoside L10(22). Conclusion: Compounds 2,3,5,8,9,16,18-22 were isolated from the fruits of P. ginseng for the first time.