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《Chinese Journal of Difficult and Complicated Cases》 2006-06
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Clinical and pathological study on 19 cases of lipid storage myopathy by muscle biopsies

BI Xue-jie,XUE Chun-mei,XUE Ping,et al.Department of Pathology,Hebei Yiling Hospital,Shijiazhuang 050091,China  
Objective To analyze the clinical and pathological characters of lipid storage myopathy.Methods The clinical characters, ECG,serum CK level,muscle strength were collected in 19 cases of lipid storage myopathy, the staining of HE,Gomori,PAS,SBB,NADH,ATPase and CA in tissue of muscle biopsies were made,the morphologic features were observed under light microscopy. Results The patients showed muscle weakness,muscle power was 3~5 grade; the level of muscle enzymes increased and the level of free lipid was abnormal in serum;the results of ECG was myogenic.Some patients' skin became thick,muscle tissue were soft and discolored. Under light microscopy,typical accumulation of lipid in muscle fibers was found.Conclusion SBB of tissue in muscle biopsies are necessary to LMS's diagnosis,but it can't distinguish types.
【CateGory Index】: R746
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