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《Chinese Journal of Difficult and Complicated Cases》 2007-01
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Comparative study of two processing methods to the infection granulation wound before operation

YAN Hong-shan,CAI Jing-long,HE Mao-wen.Department of Plastic Surgery,The Second Hospital of Shandong University,Ji'nan 250033,China  
Objective To compare the curative effect of two different processing methods to the infection granulation wound surface before operation,and seek one better method processing the infection granulation wound surface.Methods 112 patients were randomly divided into two groups.The infection granulation wound surface of 43 patients was treated by Gentamicin and 3% hypertonic saline absorbent gauze(Gentamicin group),and the others were treated by Rifampicin and 3% hypertonic saline absorbent gauze(rifampicin group).The dressings were changed 1~2 times every day .All the patients were treated by skin grafting.62 examples were flame burn patients,25 examples were burned by the aluminum,the iron,the water scald,34 examples were the hydrothermal scalds.Results In the Gentamicin group,10~14 days later,the infection granulation wound surface of 29 patients became clean,no exudation,no edema and ruddy; a small amount of secretion existed at wound surface in 14 cases.After skin grafting,the grafting skin survived completely in 29 patients,there were sporadic wound surface in all patients.In the rifampicin group,7~9 days later,the infection granu lation wound surface of 63 patients became clean,no exudation,no edema;a small amount of secretion existed at wound surface in 3 cases.After skin grafting,the grafting skin survived completely in 63 patients,there were sporadic wound surface in 3 patients.There were significant difference btween two groups (P0.05).Conclusion Two methods all are effective,but the effects of rifampicin group are more obvious than those of Gentamicin group.
【CateGory Index】: R644
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