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《Chinese Journal of Difficult and Complicated Cases》 2007-12
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The effect of Shensongyangxin capsule on P max and Pd in patients with essential hypertension complicated by paroxysmal atrial fibrillation

CAO Gui-qiu,REN Sheng-sheng,HUANG Qiang,et al.Department of Cardiology,The Fifth Affiliated Hospital,Xinjiang Medical University,Xinjiang,Urumqi 830011,China  
Objective To investigate the effect of Shensongyangxin capsule on the maximum P wave duration(Pmax)and P wave dispersion(Pd)in patients with essential hypertension(EH)complicated by paroxysmal atrial fibrillation(PAF).Methods 38 patients with EH complicated by PAF were treated by Shensongyangxin capsule,1.6g once,3 times a day,with a treatment course of 4 weeks.The changes of Pmax and Pd in treatment group before and after treatment were observed and compared with those of 40 EH patients without PAF(control group).Results Pmax and Pd in treatment group before treatment were(124±13)ms,(49±12)ms respectively,which were significantly prolonged,as compared with(110±8)ms,(31±9)ms in control group(P0.01).After 4-week treatment the attack rate in treatment group were decreased obviously and effective rate was 76.3%.Pmax and Pd [(115±12)ms,(35±12)ms] were significantly shortened,as compared with those before treatment(P0.05),however,there was no significant difference,as compared with those of control group after treatment(P0.05).Conclusion Pmax and Pd in patients with EH complicated by PAF prolong significantly,as compared with those of EH patients without PAF.Shensongyangxin capsule can shorten Pmax and Pd after 4-week and can reduce the attack of PAF.
【CateGory Index】: R259
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