Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Difficult and Complicated Cases》 2008-08
Add to Favorite Get Latest Update

The expression and significance of B cell lymphoma/leukemia-2 in adenomyosis

LIU Su-qiao,HUO Yan,SHEN Li-ying,et al.Department of Obstetrics and Gynecology,the Second Hospital of Shijiazhuang,Hebei,Shijiazhuang 050051,China  
Objective To investigate the expression of B cell lymphoma/leukemia-2(Bcl-2) in uterine endometria(functional layer),the endometrial myometrial interface(EMI) and ectopic endometrium of adenomyosis.Methods The expression of Bcl-2 in functional laryer,EMI and ectopic endometrium was detected by immunohistochemistry streptavidin biotin peroxidase(SP) in 40 samples of endometria(and myometrial) with adenomyosis(20 samples at proliferative phase,20 samples at secretory phase).Results It showed that the expression of Bcl-2 in EMI endometrial glandular cells was positive at prolifertive through early secretory stage and peaked at the end of proliferative stage,but negative at late secretory stage.The expression in EMI and ectopic foci were higher than that of functional layer(P0.05).The expression in EMI at proliferative stage was higher than that of secretory stage(P0.05).The expression of Bcl-2 in glandular cells showed no difference between EMI and ectopic foci(P0.05).Conclusion The expression of Bcl-2 in ectopic glandular cells was similar with that of EMI.It showed that ectopic glandular cells in adenomyosis probably originated from EMI.
【Fund】: 河北省卫生厅医学研究重点课题(No.06126)
【CateGory Index】: R711.71
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 2 Hits
1 JIN Hai-yan, WANG Zi-neng, XU Jian-ping (Dept. of Gynecology & Obstetrics,First Affiliated Hospital of JNUMC, Guangzhou 510632, China)[;Bcl-2 expression in eutopic endometrium and uterine adenomyotic tissue[J];Journal of Jinan University(Natural Science & Medicine Edition);2000-04
2 ZHANG Shui-rong1,ZHONG Gang2.(Dept Obstitrat & Gynecol of Jinzhou Central Hospital,434000);Relationship of apoptosis and its regulating protein Bcl-2,Bax expression to pathogenesis of endometriosis.[J];Chinese Journal of Birth Health & Heredity;2007-11
【Co-citations】
Chinese Journal Full-text Database 6 Hits
1 WANG Jin-hua~1 QIU Ru-qing~2 (1.The eighty-eight hospital of People's Liberation Army,Taian,Shandong 271000,China; 2.The First Affiliated Hospital,FCTCM,Fuzhou,Fujian 350004,China);Relationship between Kidney Deficiency,Blood Stasis and Endometrial Pathologic Change,Expression of Bcl-2 and Bax in Metrorrhagia and Metrostaxis[J];Journal of Fujian College of Traditional Chinese Medicine;2007-01
2 XUE Qing , ZENG Cheng , PENG Chao , YANG Xiuli , SUN Xiao , ZHOU Yingfang.(Department of Obstetrics and Genecology , First Hospital of Beijing University , Beijing100034 , China);Study of cell apoptosis and Bcl-2 expressions in the ectopic nidus of adenomyosis[J];Chinese Journal of Clinical Obstetrics and Gynecology;2012-05
3 JIN Hai-yan, WANG Zi-neng (Dept. of Obstetrics & Gynecology, First Affiliated Hospital of JNUMC, Guangzhou 510630,China);Expression of bcl-2 gene and its protein in gynecological diseases (A review)[J];Journal of Jinan University(Natural Science & Medicine Edition);2001-06
4 LIAO Qian-he~1, HU Shu-hong~2, CHEN Li-qiong~2, WU Wen-zhen~1, RUAN Rong-he~1, CAI Yu-qing~2, XIA Kang~1( ~1Department of Pathology, ~2Department of Obstetrics and Gynecology, Third Affiliated Hospital, Wenzhou Medical College, Ruian 325200, China);Expressions of estrogen receptor, progesterone receptor and bcl-2 in adenomyosis uterus[J];Chinese Journal of Clinical and Experimental Pathology;2006-06
5 Huang Fengying1,Zou Ying2,Wang Huanping3,et al.1.Department of Obstetrics and Gynecology,Second Xiangya Hospital,Central South University,Changsha 410011;2.Hunan Obstetric and Gynecology Hospital;3.Department of Obstetric and Gynecology,People's Hospital,Henan Province;Effect of GnRHⅡon apoptosis of the stromal cells from endometriosis in vitro[J];Progress in Obstetrics and Gynecology;2010-06
6 Liu Lan,Wang Yuanpei,Shi Zuolin,et al.Department of Obstetrics and Gynecology,Fujian Provincial Hospital,Fuzhou 350001, China;Effects of apoptosis on th endometrium at menstrual phase in patients with luteal phase defect.[J];Chinese Journal of Practical Gynecology and Obstetrics;2001-12
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1  Lai Dongmei,Zhu Guanzhen,Feng Youji,et al.Obstetric and Gyneocologic Hospital of Shanghai Medical University,200011.;Bcl-2 oncogene persistent expression in endometrial carcinoma and its clinical significance.[J];CURRENT ADVANCES IN OBSTETRICS AND GYNECOLOGY;1998-03
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved