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《Chinese Journal of Difficult and Complicated Cases》 2008-09
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The relationship between lymph node metastasis and expression of VEGF-C and its receptor in colorectal carcinoma

WANG Zhi-bo,ZHANG Yan-rong,LI Meng,et al.Department of General Surgical,the Second Affiliated Hospital of Hebei Medical University,Hebei,Shijiazhuang 050000,China  
Objective To explore the correlation between lymph node metastasis and expression of VEGF-C and its receptor(KDR)in colorectal carcinoma.Methods Retrospectively 74 specimen of colorectal carcinoma,36 of them were identified with lymph node metastasis and 38 of them without.The expression of VEGF-C and KDR was examined by immunohistochemistry in primary mass and metastatic lymph node.Results There was no statistical difference of VEGF-C expression between primary carcinoma and metastatic lymph nodes in metastasis cases(P0.05),while there was statistical difference in non-metastasis cases(P0.01).The similar results could be found in expression of KDR.Conclusion The increase of VEGF-C expression had closely relationship with genic mutation than micro-environment,the size of carcinoma and the density of carcinoma.The expression of VEGF-C and KDR were relatively with lymphatic metastasis in colorectal carcinoma.
【CateGory Index】: R735.3
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 ZHANG Li, WANG Zhi-qiang (Department of Medical Oncology, Cancer Center, Sun Yat-sen University,Guangzhou Guangdong,510060,China);Targeted therapy for colorectal cancer[J];China Oncology;2007-01
2 Lin Fangcai, Deng Hai. Beijing Power Hospital, Beijing 100073;Study of vascular endothelial growth factor and its receptor KDR in the progression of colorectal carcinoma[J];Medical Journal of Casc;2004-06
【Co-citations】
Chinese Journal Full-text Database 4 Hits
1 Qu Xin-yu, LIU Jun. People’s Hospital of Pingshan New District, Shenzhen 518118, Guangdong, CHINA.;Clinical analysis of 70 cases with colon cancer[J];Hainan Medical Journal;2011-03
2 ZHOU Jian1,LUO Yi-ren,WANG Yong-jie,SHEN Yi,KONG Jun(1Qingdao No.9 People's Hospital,Qingdao 266000,P.R.China);Expression of VEGF-C,D and their receptors mRNA in esophageal carcinoma promotes lymphatic metastasis[J];Shandong Medical Journal;2008-21
3 QIN Guang-yuan,HUANG Gui-lin,SHAO Jian-qiang,GUO Qing-jiang.(Department of Common Surgery,the First Affiliated Hospital of Medical College Shihezi University,Shihezi 832000,China);The Treatment Progress of Colon Cancer[J];Medical Recapitulate;2009-01
4 CHEN Qian-chao1,LIU Tao1,LI ZHi-ming2,PAN Ying1,HUANG Hong-bing1(1 Department of Pharmacy,2 Department of Internal Medicine,State Key Laboratory of Oncology in South China,Tumor Hospital Affiliated to Sun Yat-Sen University,Guangzhou 510060,China);Evaluation on clinical application of 3 novel antineoplastic antibodies[J];Chinese Journal of New Drugs;2009-18
China Proceedings of conference Full-text Database 1 Hits
1 HUANG Hong-bing,LIU Tao,LIN Zi-chao,CHEN Qian-chao,PAN Ying (Department of Pharmacy, Tumor Hospital Affiliated to Sun Yat-Sen University, Guangzhou 510060, China);Clinical application of three kinds of antineoplastic target therapy drugs[A];[C];2010
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Li Wanlang.Department of General Surgery,Liuzhou Cancer Hospital,Liuzhou 545006;Clinical significance of lateral lymphadenectomy in resection of rectal cancer[J];Journal of Coloproctological Surgery;2003-01
2 LIU Tong-jun,WANG Quan,LI Bo.Department of General Surgery,First Hospital,Jinin Hospital,Changchun 130021,China;Application of TME in radical operation of 48 cases of rectal cancer[J];Journal of Abdominal Surgery;2006-02
3 Zai Shoufeng,Wang Jian,Guo Ming,Xie Zhenbin(Department of Tumour Surgery,Xinxiang Central Hospital,Xinxiang 453000,China);The Clinical Analysis of Lateral Pelvic Lymphadenectomy for 52 Rectal Cancers[J];Journal of Basic and Clinical Oncology;2006-01
4 YU Dan~*,LI Tie-gang,YAO Hong-liang,ZHAO Hua,LIU Guo-qing,PI Zhi-ming(Department of General Surgery,Second Xiangya Hospital,Central South University,Changsha 410011,China);Relevant factors of lymphatic metastasis in rectal carcinoma[J];Journal of Central South University(Medical Sciences);2006-01
5 XU Zhaobin,XIONG Bin,ZHANG Kunlin, et al.Department of General Surgery,Hanyang Railway Center Hospital,Wuhan 430050,China;Analyze the relative factor on the metastasis rules of the lymph node in the colorectal cancer[J];Journal of Clinical Surgery;2003-02
6 ZHANG Guangyu *, ZHAO Min, XU Mingtang, YANG Yonghui,WANG Mengshan,YANG Chunzheng *State Key Laboratory of Experimental Hematology, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin 300020, China;Correlation of angiogenesis with expression of vascular endothelial growth factor and its receptors in lung carcinoma[J];Chinese Journal of Tuberculosis and Respiratory Diseases;2002-02
7 Yang Jinhua,Li Zongwen,Zhang Jiayou,et al.Department of Surgery,Traditional Chinese Medicine Hospital (Gaozhou 525200,China);Analysis of relative factors of lymph node metastasis in rectal cancer patients[J];Clinical Medicine of China;2006-01
8 WAN Yuanlian, PAN Yisheng, LIU Yucun, et al. Department of General Surgery, First Hospital, Peking University, Beijing 100034, China;Patterns of lymph node metastasis and extent of lymph node dissection for middle or lower rectal cancer: analysis of 462 cases[J];Chiese Journal of Surgery;2001-06
9 Lin Fangcai, Guan Wenzen,Tong Weiting, et al Beijing Electrotechnics Hospital (Beijing, 100073);STUDY ON THE MICROVESSEL DENSITY AND EXPRESSION OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN HUMAN COLORECTAL CANCER[J];CANCER RESEARCH AND CLINIC;1999-02
10 LIANG Jun lin,WAN De sen,PAN Zhi zhong,ZHOU Zhi wei,CHEN Gong,LU Zhen hai,LI Li ren,WU Xiao jun,DING Pei rong. Department of Abdominal Surgery,Cancer Center,Sun Yat sen University,Guangzhou 510060,China;Univariate and multivariate regression analysis of recurrence and metastasis after curative anterior resection for rectal carcinoma[J];Chinese Journal of Gastrointestinal Surgery;2004-02
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