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《Chinese Journal of Difficult and Complicated Cases》 2008-09
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Effect of parathyroid hormone on cardiac structure and function in maintenance hemodialysis patients

PEI Rong-guang,SU Ru-song,ZHENG Min-zhen,et al.Department of Nephrology,Luanxian People's Hospital,Heibei Provience 063700,China  
Objective To explore the effect of parathyroid hormone(PTH)on cardiac structure and function in maintenance hemodialysis(MHD)patients.Methods One hundred and six MHD patients were divided into L-PTH group(PTH500 pg/ml),M-PTH group(PTH range from 500 pg/ml to 800 pg/ml)and H-PTH group(PTH800 pg/ml).All cases underwent echocardiography examination.The ventricular septal thickness(IVST),left ventricular posterior wall thickness(LVPWT)and left ventricle mass index(LVMI),ejection fraction(EF)and the E/A peak ratio were calculated for assessing cardiac function.The results were compared among three groups.Results All patients were proved to be secondary hyperparathyroidism(SHPT).39,36 and 31 cases were respectively ranked in L-PTH group,M-PTH group and H-PTH group.The hemodialysis lasted longer in H-PTH group than M-PTH group and L-PTH group(P0.05 or P0.01).The values of IVST,LVPWT and LVMI in H-PTH and M-PTH group were significantly higher than L-PTH group,while the EF and the value of E/A ratio were significantly lower than L-PTH group(P0.01).Furthermore,the values of IVST,LVPWT and LVMI were obviously higher than M-PTH group,while EF and value of E/A peak ratio were lower(P0.01).Conclusion It proved that the level of PTH increased with hemodialysis time,and the cardiac Stracture and function were effected in MHD patients.
【CateGory Index】: R692.5
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【Co-references】
Chinese Journal Full-text Database 2 Hits
1 LIU Qi,CHEN Ming,CAO Ling,et al(1.Department of Nephrology,2.Department of Ultrasound,Affiliated Hospital of Luzhou Medical College,Luzhou 646000,Sichuan,China);Relationship of left ventricular mass index and serum parathyroid hormone,calcium-phosphorus product in patients with chronic kidney disease[J];Medical Journal of West China;2008-02
2 LU Xia,SANG Xiao-hong (Department of Nephrology,First Affiliated Hospital,Xinjiang Medical University, Urumqi 830011,China);The relationship between increased serum parathyroid hormone and left ventricular hypertrophy and dysfunction in patients with chronic renal disease Ⅲ[J];Journal of Xinjiang Medical University;2009-10
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 LU Jun,CHENG Xue-tao,ZHOU Xi-yu,et al.Kidney Transplant Center,Ningxia People′s Armed Police Corps Hospital,Yinchuan 750004,China;Systematic Health Management in Maintenance Hemodialysis Patients[J];Chinese General Practice;2010-18
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