Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Difficult and Complicated Cases》 2009-07
Add to Favorite Get Latest Update

The mechanism of traditional Chinese medicine Wenshenhuoxue recipe I for treatment of erectile dysfunction induced by diabetes

LIU Peng,QU Yong,TAN Chi,et al.Department of Endocrinology,The Guangxi Traditional Chinese Medical College Affiliated Ruikang Hospital,Nanning 530011,China  
Objective To explore the mechanism of the traditional Chinese medicine Wenshenhuoxue recipe I for treatment of erectile dysfunction(ED) induced with diabetes mellitus.Methods The diabetes mellitus (DM) rat model was induced by streptozotozin (STZ),and then apomorphine (APO) was administrated to set ED diabetes model.Thirty-three model rats were randomly divided into 3 groups:normal saline group (model group),Fufangfufangteng heji group(control group),and Wenshenhuoxue recipe I group (treatment group).Each group were treated with metformin(120 mg·kg-1·d-1) to control the level of blood glucose.The effects on hormone of diabetes ED rats were investigated after 8 weeks treatment and the pathologic histological changes of testis were also observed.Results The content of luteinizing hormone(LH) and testosterone(T) in treatment group were higher than that in model group and control group (P0.01). Furthermore,the layer number of spermatogenic cells,interstitial cells and sperm of testis were increased in treated group.Conclusion It demonstrated that Wenshenhuoxue recipe I could increase the serection of LH and T,improve the amount of spermatogenic cells,interstitial cells and sperm in DM rats model,and indicated that it might have better effect on erectile dysfunction.
【Fund】: 广西中医学院研究生导师课题(No.Y2007097)
【CateGory Index】: R285.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Secondary Citations】
Chinese Journal Full-text Database 5 Hits
1 Wang Weifu, Zhang Yuanfang, Ding Qiang, Xu Yizhen *, Fang Jingcong *, Kong Xianguo, Si Hongli * (Department of Urology, *Diabetes, Huashan Hospital,Shanghai Medical University, Shanghai 200040);MAKING EXPERIMENTAL ANIMAL MODELS OF IMPOTENCE WITH DIABETES MELLITUS[J];JOURNAL OF SHANGHAI MEDICA(UNIVERSITY);1998-05
2 CHOU CHUHUA;GE RENYONG AND SHE YUNCHE(Department of Physiology,Chinese Traditional Medical College,Jiangxi);EFFECTS OF L-TYROSINE ON THE FUNCTION OF REPRODUCTIVE ENDOCRINE SYSTEM IN RATS[J];Acta Physiological Sinica;1982-04
3 WANG Weifu *,ZHANG Yuanfang,DING Qiang,et al. *Department of Urology,Hainan Provincial People's Hospital,Haikou 570311;Ultrastructual studies of cavernous tissue in impotent rats with diabetes mellitus[J];CHINESE JOURNAL OF UROLOGY;1999-10
4 Wang Win;Qi Tianwei;Zhao Shengtian;et al.(Department of Urology,the Affiliated Hospital of Shandong Medical University,Jinan 250012);The role of perineal muscles in penile erection[J];CHINESE JOURNAL OF VROLOGY;1995-04
5 ZHANG Ling,WANG Yun,MAO Hai-Ting et al.Institute of Bacic Medicine, Shandong Academy of Medical Sciences,Jinan 250062;Study on the inhibition of telomerase activity and regulated mechanism in human cancer cell by Icarrin[J];Chinese Journal of Immunology;2002-03
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved