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《Chinese Journal of Difficult and Complicated Cases》 2010-06
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Comparison on the therapeutic effects of prostaglandin E and milrinone in treating ventricular septal defect combined pulmonary hypertension in child

ZHAO Xiang-dong,LU Long,CUI Zhen-tian.Zone One,the Centre of Heart and Lung,General Hospital of Beijing Military Region,Beijing 100700,China  
Objective To compare the effect of prostaglandin E(PGE) and milrinone(Mil) on children with ventricular septal defect combined pulmonary hypertension.Methods 30 patients with ventricular septal defect combined pulmonary hypertension were received Mil(Mil group) or PGE(PGE group) intravenously after unloosen the aorta during the operation.The mechanical ventilation time,LVEF and pulmonary pressure measured by ultrasound 10 days after operation were recorded.Results Compared with pre-operation,the pulmonary pressure decreased significantly after operation in the two groups(P0.05).LVEF didn't have significant changes.Mechanical ventilation time,pulmonary pressure and LVEF didn't have significant statistical changes between the two groups(P0.05). Conclusion Compared with Mil,PGE has similar effect of decreasing pulmonary pressure in ventricular septal defect repair operation but less side effect.
【CateGory Index】: R726.5
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Chinese Journal Full-text Database 1 Hits
1 LU Jie,ZHANG Da-dong (Minhang Hospital of Ruijin Hospital Group,Shanghai 201100, China);Progress of Prostaglandin E1 in Treating Pulmonary Hypertension[J];Advances In Cardiovascular Diseases;2004-S1
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