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《Chinese Journal of Difficult and Complicated Cases》 2010-07
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The effects of sevoflurane compound the small dose of lidocaine on postoperative analgesia and intestinal function recovery after esophageal cancer operation in elderly patients

NIE Bin,YANG Ming-hua,LIN Zhi- ping.Department of Anesthesiology,Teaching Hospital of Fujian Medical University/Fujian Provincial Tumor Hospital, Fuzhou 350014,China  
Objective The study was aimed to explore the effects of sevoflurane compound small dose of lidocaine on postoperative analgesia and intestinal function recovery after esophageal cancer operation in elderly patients. Methods Sixty cases with esophageal cancer from September 2009 to March 2010 were divided into lidocaine group and saline group randomly.Both two groups received intraoperative sevoflurane based anesthesia,followed with 1.5 mg·kg~(-1)·h~(-1) lidocaine intravenous injection at anesthesia induction phase(lidocaine group),or same dose of saline(saline group).The 12h and 24h post-operative morphine consumption and postoperative visual analogue pain score,as well as the time of first flatus and stool were recorded.Results In lidocaine group,the postoperative visual analogue pain socre was decreased than saline group,together with the 12h and 24h postoperative morphine consumption and the time of first flatus and stool(P0.05).Conclusion It demonstrated that the sevoflurane compound small dose of lidocaine on esophageal cancer operation in elderly patients could reduce the pain after operation,and relieved the intestinal function could be quickly recovered.
【CateGory Index】: R614
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