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《Chinese Journal of Difficult and Complicated Cases》 2013-01
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The study of blood coagulation status in type 2 diabetes mellitus

MU Zhi-jing,WANG Li.Department of Endocrinology, Xuanwu Hospital,Capital Medical University,Beijing 100053,China  
Objective To explore the changes and clinical significance in coagulation anti-coagulation and fibrinolysis system in patients with type 2 diabetes mellitus(DM).Methods To measure thrombin time(TT),activated partial thromboplastin time(APTT),prothrombin time(PT),and fibrinogen(Fib),anti-thrombinⅢ(AT-Ⅲ),protein C(PC),protein S (PS)in 311 patients with type 2 diabetes mellitus from 2010 to 2011.These patients were categorized as single DM group, DM with hypertension group,DM with coronary heart disease group.At the same time,30 healthy people were selected as contrast group.SPSS software was used for statistic analysis.Results The activity of AT-Ⅲ,PC,PS of type 2 diabetes mellitus were progressively lower than those of control group.There was a significant difference between single DM group and DM with coronary heart disease group.The level of APTT,PT had shortened compared with normal controls.The level of plasma Fib of type 2 diabetes had raised significantly than that of normal controls.Conclusion Coagulation function was disordered in patients with type 2 diabetes mellitus;especially those with vascular complications.AT-Ⅲ,PC,PS,APTT,PT,Fib were helpful for evaluating coagulation function.It would be important for the diagnosis and therapy of hyper-coagulable state in DM patients.
【CateGory Index】: R587.1
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 HU Yi,CHEN Si-jiao,LI Hong-yan,et al.Teaching and Research Office for Geriatric Disease of the First Affiliated Hospital of China Medical University,Shenyang 110001,China;Impact on Coagulation and Metabolic Indicators by Overweight and Obesity in Pateints with Type 2 Diabetes Mellitus[J];Chinese General Practice;2011-05
2 PENG Dezhen Department of Laboratory,the Affiliated Hospital of Guilin Medical College,Guangxi Zhuang Autonomous Region,Guilin 541001,China;Clinical significance of antithrombin Ⅲ and D-dimer testing in patients of gestational diabetes mellitus[J];China Medical Herald;2012-10
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 DU Tong-xin, WANG Zi-zheng (RIA Center, Nanjing First Hospital Affiliated to Nanjing Medical University, Nanjing 210006, China);Measurement of Insulin and C-peptide Excitatory Test Levels in Gestational Diabetes Mellitus[J];Labeled Immunoassays and Clinical Medicine;2001-04
2 LI Hong,LI Jia-xuan,ZHANG Zhi-zhe,HUANG Tian-xia(The First Hospital of Nanning City,Guangxi Nanning 530022,China);Changes of CD4~+ CD25~+ Regulatory T Cells in Peripheral Blood of Diabetes Mellitus Complicated with Pulmonary Infection and Its Significance[J];Guangxi Medical Journal;2011-02
3 DING Xuemei.Department of Emergency,People's Hospital of Tianjin Wuqing District,Tianjin 301700;The characteristics of metabolism disorder and the changes of serum homocysteine(tHcy) level in patients with obese type 2 diabetes mellitus[J];Hebei Medical Journal;2008-05
4 CHEN Sijiao~1 GAO Yang~1 HU Yi~1 WEI Min~1 LI Qiang~2 ZHANG Shaowei~3 SONG Jindan~4 1 Teaching and Research Office for Geriatric Disease, 2 Endocrinology Laboratory,The First Affiliated Hospital of China Medical University,Shenyang 110001,China; 3 Department of Endocrinology and Kidney Internal Medicine,No.202 Hospital of PIA,Shenyang 110001,China; 4 Medical Molecular Biology Research Institute of China Medical University-Key Laboratory of Cell Biology of Ministry of Health,Shenyang 110001,China;Effects of sulodexide on early diabetic nephropathy[J];Chinese Journal of Clinical Pharmacy;2008-01
5 CHEN Si-jiao,QI Hong,WEI Min,et al.Department of Leader-treating,the First Affiliated Hospital,China Medical University,Shenyang 110001,China;Effect of Losartan on C-Reactive Protein and Sexual Function in Patients with Hypertension and Diabetes Merging Insulin Resistance and Erectile Dysfunction[J];Chinese General Practice;2007-18
6 HU Yi,LIU Li-min,ZHANG Bin,et al.Teaching and Research Office for Geriatric Disease of the First Affiliated Hospital of China Medical University,Shenyang 110001,China;Effect of Aldosterone Antagonist on IRI and CRP in Patients with Metabolic Syndrome Complicated by Chronic Heart Failure[J];Chinese General Practice;2008-15
7 ZHANG Yan-hong,YANG Wei,FENG Ming.Department of Gerontology,Xuanwu Hospital,Capital Medical University,Beijing 100053,China;Relationship between Resistin and Insulin Resistance,Obesity and Type 2 Diabetes[J];Chinese General Practice;2010-36
8 SHI Qing,MAO Jianping,WANG Minmin,et al. Department of Gynecology and Obstetrics, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China;Study of early laboratory diagnosis of disseminated intravascular coagulation in postpartum hemorrhage[J];Shanghai Medical Journal;2002-10
9 XIONG Ying,CHEN Si-jiao,GAO Yang,WEI Ming,HU Yi,WANG Dong-hui,ZHANG Shao-wei,SONG Jin-danTeaching and Research Office for Geriatric Disease of the First Affiliated Hospital of China Medical University,Shenyang,Liaoning,110001,China;Study on NF-κB activation in the pathogenesis of atherosclerosis in diabetic rats[J];Chinese Journal of Cardiovascular Rehabilitation Medicine;2008-01
10 CHEN Si-jiao,WEI-min,LI Ting-fu,et al.Department of Geriatrics,The First Affiliated Hospital,China Medical University,Shenyang 110001,China;The relationship of levels of resistin,leptin and C-reactive protein with body weight and insulin resistance in patients with metabolic syndrome[J];Chinese Journal of Diabetes;2008-08
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