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《Chinese Journal of Difficult and Complicated Cases》 2013-01
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A case control study of the retrograde catheter directed thrombolysis in treating acute iliofemoral venous thrombosis

WANG Zhi-bo,LI Meng,ZHANG Feng,et al.Department of Vascular Surgery,The Second Hospital of Hebei Medical University, Hebei,Shijiazhuang 050000,China  
Objective To investigate the efficacy of retrograde catheter directed thrombolysis through femoral vein of unaffected limb in treating acute iliofemoral venous thrombosis.Methods 27 patients with acute iliofemoral deep venous thrombosis diagnosed by mode B ultrasound were divided into Group A(patients treated with catheter directed thrombolysis, n=12)and Group B(patients treated with systemic thrombolytic,n=15).The reduction of the affected limb perimeter and long term function of valve of both groups were observed and compared.Results After 14 days treatment,the differences of the reduction of lower limb perimeter between Group A and Group B(3.4 cm±0.8 cm for Group A and 2.8 cm±0.8 cm for Group B)are of no statistical significance(P 0.05).After 6 months treatment,the deep venous valve function was evaluated by photoplethysmography(PPG)with the results that the venous refill time(VRT)were 22.2 s±3.5 s for Group A and 16.6 s±4.Is for Group B,and the differences between them are statistically significant(P 0.05).Conclusion Retrograde catheter directed thrombolytic through femoral vein of unaffected limb in treating acute iliofemoral venous thrombosis can effectively improve the deep venous valve function and reduce the incidence of complications of venous thrombosis.
【CateGory Index】: R654.4
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