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《Chinese Journal of Difficult and Complicated Cases》 2017-02
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Therapeutic effect of prednisone and Guilongtongluo capsules on chronic inflammatory demyelinating polyneuropathy

ZHOU Jin;SUN Yuhua;HAN Yi;WANG Bing;LI Xiaoyan;LIU Xiao;Department of Neurology,Xinhua Hospital,Dalian University;  
Objective To explore the clinical effect of prednisone combined with Guilongtongluo capsules in the treatment of chronic inflammatory demyelinaliug polyneuropathy.Methods A total of 76 cases from January 2012 to February2015 in Dalian University Affiliated Xinhua Hospital which were diagnosed and received the treatment of chronic inflammatory demyelinating polyneuropathy patients were randomly divided into control group(given prednisone tablets 15 mg/d) and observation group(given prednisone tablets 15 mg/d + Guilongtongluo capsules 6 pills / time,3 times /d) with 38 cases in each group.The clinical efficacy of the 2 groups before and after treatment of upper limb distal and proximal,distal and proximal lower limb muscle strength were observed;the EMG / evoked potential were examined in 2 groups of patients before and after treatment of ulnar nerve,common peroneal nerve motor nerve conduction velocity(MCV),distal latency(ML) and sensory nerve conduction velocity(SCV) were evaluated before and after treatment,the motor function and sensory function,the evaluation of the ability of daily file of patients with Barthel index(ADL) changes and adverse reactions during treatment were compared.Results The total efficiency of the observation group was significantly higher than the control group(92.11%vs.68.42%,x~2=6.79,P =0.03).Alter treatment,2 groups of patients with upper limb distal and proximal,distal and proximal lower limb muscle strength was significantly higher than before treatment(Control group;t=9.76,t=6.99,t=7.85,t=4.69,P 0.01,observation group:t=8.36,t=7.82,t = 8.02,t=5.82,P 0.01).and the observation group was higher than that of the control group(t =11.02,t=10.22,t=6.68,t=11.14,P 0.01).2 groups of patients with ulnar nerve and common peroneal nerve MCV,SCV higher than that before treatment,ulnar nerve and peroneal nerve ML was significantly lower than that before treatment,and the observation group MCV,SCV higher than the control group,ML was lower than the control group(t = 6.17,t =7.77,t =7.98,t =6.51,t =4.96,t =7.18,P 0.01).The scores of motor function and sensory function of the 2 groups were lower than those before treatment,while the scores of the observation group after treatment were lower than those of the control group(t =9.36,t= 6.72,P 0.01).2 groups of patients after treatment ADL score was significantly higher than before treatment(t =4.36,t =5.24,P 0.05),the observation group after treatment ADL score was significantly higher than that of the control group(t =9.66,P 0.01);2 groups had no significant adverse reactions during treatment.Conclusion Prednisone combined with Guilongtongluo capsules in the treatment of chronic inflammatory demyelinating polyneuropathy has a significant effect and safety.
【CateGory Index】: R744.5
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【References】
Chinese Journal Full-text Database 1 Hits
1 FU Youchun;Department of Traditional Chinese Medicine, Guizhou Provincial People's Hospital;;Rehabilitation and Treatment of Chronic Inflammatory Demyelinating Multiple Nerve Root Neuropathy[J];中国卫生标准管理;2018-03
【Citations】
Chinese Journal Full-text Database 6 Hits
1 WU Xuan;LIN Aiyu;WANGHuayan;WEI Huixing;WANG Danni;WANG Ning;Department of neurology, the First Affiliated Hospital of Fujian Medical University;;An open label study of the effects of oral prednisone on neuromyelitis optica[J];中国神经精神疾病杂志;2015-03
2 ;Intracranial inflammatory demyelinating disease associated with chronic inflammatory demyelinating Polyradiculoneuropathy:a report of one case[J];中华神经医学杂志;2014-07
3 JIANG Ya-fen;YIN Hou-min;YU Jian-jun;Department of Neurology,the Second Affiliated Hospital of Medicine School,Zhejiang University;;Effect of Autonomic Nervous System Damage of Chronic Inflammatory Demyelinating Polyradiculoneuropathy on Sympathetic Skin Response and Autonomic Symptom Profile Score[J];中国全科医学;2013-41
4 ZOU Lihua;CHEN Xiaodan;ZOU Lianxia;ZENG Qingxiang;LI Hui;YE Zhiguang;Department of Neurology, Longgang People's Hospital of Shenzhen City;Department of Traditional Chinese Medicine, Longgang People's Hospital of Shenzhen City;Department of Integrated Traditional and Western Medicine, Longgang People's Hospital of Shenzhen City;;Clinical effect of Shufenghuayutongluo Decoction combined with hyperbaric oxygen in treating migraine and its influence on hemodynamics and serum magnesium[J];中国医药导报;2013-31
5 ZHAO Dong-hong,WANG Ke-ren,ZHU Dan,et al.(Department of Neurology,First Hospital of Jilin University,Changchun,Jilin 130021,China);Electrophysiological features of acute inflammatory demyelinating polyneuropathy and chronic inflammatory demyelinating polyneuropathy[J];中风与神经疾病杂志;2013-04
6 XIA De-yu (Navy General Hospital,Beijing 100048,China);Clinical observation on effects of treating chronic inflammatory demyelinating poIyneuropathy by traditional Chinese medicine combined with western medicine[J];海南医学院学报;2013-08
【Co-citations】
Chinese Journal Full-text Database 5 Hits
1 Hu Chengbao;Longping Township Health Hospital of Jianshi County,Hubei Province;;Clinical curative effect of modified Tongqiao Huoxue decoction in the treatment of headache of internal injury and ecchymosis[J];中国社区医师;2018-09
2 HUANG Xinxin;DING Jie;YU Lu;ZHU Desheng;GUAN Yangtai;Department of Neurology,Changhai Hospital, Second Military Medical University;;Correlation study on elevated cholesterol level and the risk of relapse in patients with neuromyelitis optica spectrum disorders[J];中国神经精神疾病杂志;2017-11
3 Wang Fang;Yao Yuanrong;Department of Neurology, General Hospital of Tianjin Medical University;Department of Neurology, People's Hospital of Guizhou Province;;Recent advances in combined central and peripheral demyelination[J];中华神经医学杂志;2017-09
4 JIA Kun;LIU Xiaojiao;ZHOU Bingjie;ZHANG Daqi;YANG Li;Department of Neurology and Tianjin Neurological Institute, Tianjin Medical University General Hospital;;The study on the association of serum interleukin-27 levels with disease severity in neuromyelitis optica[J];中国神经精神疾病杂志;2017-08
5 ZHOU Jin;SUN Yuhua;HAN Yi;WANG Bing;LI Xiaoyan;LIU Xiao;Department of Neurology,Xinhua Hospital,Dalian University;;Therapeutic effect of prednisone and Guilongtongluo capsules on chronic inflammatory demyelinating polyneuropathy[J];疑难病杂志;2017-02
【Co-references】
Chinese Journal Full-text Database 4 Hits
1 MA Yan;LU Ming;FAN Dongsheng;Department of Neurology,Third Hospital,Peking University;;The features of an anti-NF155 IgG4 antibodies positive chronic inflammatory demyelinating polyradiculoneuropathy patient and a literature review[J];中国神经免疫学和神经病学杂志;2017-03
2 SUN Rui-Di;FU Bing;JIANG Jun;Department of Electrophysiology,Wuhan Women and Children's Hospital;;Role of short-latency somatosensory evoked potential in the diagnosis of chronic inflammatory demyelinating polyneuropathy[J];中国当代儿科杂志;2017-05
3 ZHOU Jin;SUN Yuhua;HAN Yi;WANG Bing;LI Xiaoyan;LIU Xiao;Department of Neurology,Xinhua Hospital,Dalian University;;Therapeutic effect of prednisone and Guilongtongluo capsules on chronic inflammatory demyelinating polyneuropathy[J];疑难病杂志;2017-02
4 LIU Jingjie;HAN Ping;GAO Zhen;GONG Fuhua;MA Xiaolin;XIANG Li;Department of Neurology,the Second Affiliated Hospital,Xi’an Jiaotong University;;Comparison of clinical manifestations and electrophysiological features in patients with chronic inflammatory demyelinating polyneuropathy and Type-I Charcot Marie Tooth Disease[J];中国神经精神疾病杂志;2016-08
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 ZHAO Shuqin Pharmacy of Chinese Medicine Room,Hospital Affiliated Nongan Health Workers Specialized Secondary Schools, Nongan 130200,China;Pharmacological action and clinical application of Gegen[J];中国医药科学;2013-02
2 LIN Aiyu,CHEN Fuyong,WANG Xiaoyi,LI Zhiwen,CHEN Mingfeng.Department of neurology,Department of neurosurgery,the first affiliated hospital of Fujian Medical University,Fuzhou 350005,China.;Detection of cognitive impairment with multiple sclerosis and it's influencing factors[J];中国神经精神疾病杂志;2012-10
3 GUANG Ri-jun,HUANG Long-hua(Funing county hospital of Chinese medicine Jiangsu Province,Jiangsu Funing 224 400);Qufeng Blood Circulation to Resolve the Soup Together Heart-Protecting Musk pill in Treatment of Migraine in Clinical Research Pipe the Japanese[J];辽宁中医杂志;2012-10
4 LI Ai-Hong (Department of Chemical Engineering,Chengde Petroleum College,Chengde,Hebei 067000,P.R.China);Content Analysis of Zinc,Copper,Manganese,Iron and Magnesium in Five Kinds of Anti-Liver Cancer Chinese Herbal Medicines[J];光谱实验室;2012-04
5 REN Lijuan QIAO Hong GAO Lei The Fifth People's Hospital,Ningxia Hui Autonomous Region,Dawukou 735000,China;Clinical observation on Yindan Xinnaotong Soft Capsule combined with Sibelium in the treatment of cephalagra[J];中国医药导报;2012-04
6 Gao Yongwei (Shanxi Economic and Trade School,Taiyuan Shanxi 030012);On the Characteristics of 56 Kinds of Commonly Used Medical Chinese Herbal Medicine Magnesium Content and Their Health Care Function Application[J];搏击(体育论坛);2012-01
7 Li Gang,Liu Shuxin,Xu Jun,et al.Department of Neurology,Henan Provincial People's Hospital,Zhengzhou 450003,China;Analysis of the juvenile with chronic inflammatory demyelinating polyneuropathy[J];中国实用神经疾病杂志;2011-24
8 XIE Xing-liang1, SHENG Yan-mei1, HAN Li2, YANG Ming3 (1.Pharmacological College,Chengdu Medical University,Chengdu 610083,China;2.Pharmacological College,Chengdu University of Traditional Chinese Medicine,Chengdu 611173,China;3.Key Laboratory of Modern TCM Preparation,Ministry of Education,Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China);Effect of Astragalus Polysaccharides Extract from Different Sources on Lymphocyte Proliferation and its Chemical Composition Analysis[J];时珍国医国药;2011-11
9 JIA Xia-pei,WANG Xiao-ping,FENG Ya-juan,et al.Department of Physical Therapy,First Hospital of Handan City,Hebei Province,Handan 056002,China;Review on the clinical research of auricular acupuncture points in treating migraine during recent[J];环球中医药;2011-06
10 CAO Lei Department of Acupuncture and Moxibustion,Beijing Shijitan Hospital,Beijing 100038,China;Observation on therapeutic effect of acupuncture in the treatment of no-premonitory migraine at acute stage[J];中国医药导报;2011-28
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