Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Difficult and Complicated Cases》 2017-03
Add to Favorite Get Latest Update

Progress of clinical application of mesenchymal stem cells in the treatment of Crohn's disease

SU Lele;DONG Weiguo;Department of Gastroenterology,Renmin Hospital of Wuhan University;  
Crohn's disease(CD) is a inflammatory,chronic,lifelong disease disorders that affect the gastrointestinal tract.It is one type of inflammatory bowel diseases(IBD),and its pathogenesis is not very clear at present.But generally it is considered related to immune,genetic,environmental,and other infections.The current drugs used for IBD mainly are the drugs that suppress inflammation and regulate the immunity.They have some limitations and many side effects.In recent years,stem cell therapy gradually got into the line of sight of the researchers,become a hot topic of current research.Mesenchymal stem cells(MSCs) have become one of the most promising therapies for the treatment of Crohn's disease because of its strong ability of self replication and differentiation,as well as the regulation of immune and inflammatory responses.This article reviews the clinical application of mesenchymal stem cells in the treatment of CD.
【CateGory Index】: R574.62
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 3 Hits
1 Damian Garcia-Olmo;Hector Guadalajara;Ines Rubio-Perez;Maria Dolores Herreros;Paloma de-la-Quintana;Mariano Garcia-Arranz;Hospital Fundación Jimenez Díaz;Colorectal Surgery Unit,University Hospital Fundación Jiménez Díaz;Colorectal Surgery Unit,La Paz University Hospital;Cell Therapy Laboratory,University Hospital Fundación Jiménez Díaz;;Recurrent anal fistulae:Limited surgery supported by stem cells[J];World Journal of Gastroenterology;2015-11
2 He Xiao-wen;Chen Ze-xian;Zhang Long-juan;He Xiao-sheng;Lian Lei;Ke Jia;Lin Xu-tao;Chen Xi;Wu Xiao-jian;Lan Ping;Department of Colorectal and Anal Surgery, the Sixth Affiliated Hospital, Sun Yat-sen University;Laboratory of General Surgery, the First Affiliated Hospital, Sun Yat-Sen University;;Efficacy and oncological safety of bone marrow mesenchymal stem cell transplantation for colitis in inflammatory bowel disease models in mice[J];中国组织工程研究;2014-23
3 Wei Zhao, Jun-Jie Li, Da-Yong Cao, Xiao Li, Lin-Ying Zhang, Yong He, Shu-Qiang Yue, De-Sheng Wang, Ke-Feng Dou, Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi’an 710032, Shaanxi Province, China;Intravenous injection of mesenchymal stem cells is effective in treating liver fibrosis[J];World Journal of Gastroenterology;2012-10
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Feng Lanyan;Zhang Dazhi;Department of Infectious Diseases, The Second Hostipal, Affiliated to Chongqing Medical University;;Clinical application of mesenchymal stem cells in treatment of acute-on-chronic liver failure and related research advances[J];中华肝脏病杂志;2017-09
2 Chen Li;Chen Song;Tianjin Eye Hospital,Clinical College of Ophthalmology of Tianjin Medical university,Tianjin Key Lab of Ophthalmology and Visual Science,Tianjin Institute of Ophthalmology;;Research progress of mesenchymal stem cells for the treatment of diabetic retinopathy[J];中华实验眼科杂志;2016-07
3 Shen Jiankun;Zheng Lianqiu;Pan Xingnan;Clinical Liver Disease Researcher Centre,180th Hospital of PLA,Nanjing Military Command;;Efficacy of intrahepatic transplantation of autologous bone marrow mesenchymal stem cells in the treatment of patients with decompensated alcohol-induced liver cirrhosis[J];实用肝脏病杂志;2015-06
4 FU Qing-song;XIA Yu-jun;ZHANG Ming;LIU Ming;SHAN Shou-qin;Department of Anatomy,Medical College of Qingdao University;The 1st Sanatorium of Qingdao,PLA Jinan Military Area Command;;Transplantation with three-dimensional spheroid-cultured mesenchymal stem cells down-regulates expression of TNF-αand apoptosis-related proteins in rats with cerebral ischemia/reperfusion injury[J];第二军医大学学报;2015-08
5 Yi Cao;Tao Liu;Ming-Li Yin;Bo-Ya Zhang;Hong-Li Song;the First Central Clinical College, Tianjin Medical University;Department of Organ Transplantation, Tianjin the First Central Hospital;Tianjin Key Laboratory of Organ Transplantation;;Role of CX3CR1 in repair of injured intestinal epithelial cells by bone marrow mesenchymal stem cells[J];世界华人消化杂志;2015-23
6 YI Min;FU Bi-mang;ZHANG Jie;Department of Hepatobiliary Surgery,the Second Affiliated Hospital of Kunming Medical University;;Research Progress in Mesenchymal Stem Cell Transplantation in Patients with Liver Cirrhosis[J];医学综述;2015-15
7 OU Yan-fang;Clinical Laboratory,Jingyang Hospital of Maternal and Child Healthcare;;Peripheral blood lymphocyte subsets of patients with inflammatory bowel disease before and after drug treatment activities[J];安徽医药;2015-07
8 LIAN Liying;QU Bo;JIN Shizhu;ZHU Fang;TONG Jiazhao;Department of Gastroenterology,the Second Affiliated Hospital of Harbin Medical University;;Bone marrow mesenchymal stem cells and stem cell factors in the treatment of inflammatory bowel disease[J];胃肠病学和肝病学杂志;2015-05
9 Chen Jian-hua;Hu Xiang;Department of Pharmacology,School of Pharmacy,North Sichuan Medical College;Shen Zhen Beike Biotechnology Company;;Umbilical cord mesenchymal stem cell transplantation for liver cirrhosis:a repeated measurement analysis[J];中国组织工程研究;2015-19
10 YAN Xiaoming;ZHANG Liting;LUO Jingyi;Institute of Infection,The First Hospital of Lanzhou University;;Therapeutic effect of estradiol-pretreated human bone marrow mesenchymal stem cells on liver cirrhosis in mice[J];临床肝胆病杂志;2015-03
【Secondary Citations】
Chinese Journal Full-text Database 8 Hits
1 Haig Dudukgian,Herand Abcarian,Department of Colorectal Surgery,John Stroger Hospital of Cook County,IL 60612,United States Herand Abcarian,Department of Surgery,University of Illinois Chicago,IL 60612-4325,United States;Why do we have so much trouble treating anal fistula?[J];World Journal of Gastroenterology;2011-28
2 Fu Bi-mang1,Su Ying-zhen2,He Xiao-wen3,Hu An-bin4,He Xiao-shun4,Huang Jie-fu4 1Department of Hepatobiliary Surgery,Second Affiliated Hospital of Kunming Medical College,Yunnan Institute of Hepatobiliary Surgery,Kunming 650101,Yunnan Province,China;2Department of Epidemiology,Institute of Tropical Public Health,Southern Medical University,Guangzhou 510000,Guangdong Province,China;3Department of Colorectal Surgery,Sixth Affiliated Hospital of Sun Yat-sen University,Guangzhou 510655,Guangdong Province,China;4First Affiliated Hospital of Sun Yat-sen University,Guangzhou 510080,Guangdong Province,China;A rapid method for harvesting murine bone marrow cells using retrograde isolation of the femur and tibia[J];中国组织工程研究与临床康复;2011-14
3 Margie Lee CLAPPER~(2,4),Harry Stanley COOPER~3,Wen-Chi Lee CHANG~2 Divisions of ~2 Population Science and ~3 Medical Science,Fox Chase Cancer Center,Philadelphia,PA 19111,USA;Dextran sulfate sodium-induced colitis-associated neoplasia:a promising model for the development of chemopreventive interventions[J];Acta Pharmacologica Sinica;2007-09
4 Xin-Qin Kang,Tu-Sheng Song, Department of Genetics and Molecular Biology, Medical School of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China Wei-Jin Zang, Dong-Ling Li, Xiao-Li Xu, Xiao-Jiang Yu, Department of Pharmacology, Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education, School of Medicine, Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China Li-Jun Bao, Department of Obstetrics and Gynecology, First Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China;Fibroblast growth factor-4 and hepatocyte growth factor induce differentiation of human umbilical cord blood-derived mesenchymal stem cells into hepatocytes[J];World Journal of Gastroenterology;2005-47
5 Dong-Chang Zhao, Rui Chen, Wei-Hua Yu, Xiu-Ming Zhang, Shu-Nong Li, Peng Xiang, Center for Stem Cell Biology and Tissue Engineering, Sun Yat-Sen University, 74# Zhongshan Road II, Guangzhou 510080, Guangdong Province, China Dong-Chang Zhao, Jun-Xia Lei, Wei-Hua Yu, Xiu-Ming Zhang, Shu-Nong Li, Department of Pathophysiology, Medical School of Sun Yat-Sen University, 74# Zhongshan Road II, Guangzhou 510080, Guangdong Province, China Dong-Chang Zhao, Department of Pediatrics, Guangdong Province Maternal and Children's Hospital, 13# Guangyuan Xilu, Guangzhou 510010. Guanedone Province. China;Bone marrow-derived mesenchymal stem cells protect against experimental liver fibrosis in rats[J];World Journal of Gastroenterology;2005-22
6 Wei-Da Zheng, Li-Juan Zhang, Mei-Na Shi, Zhi-Xin Chen, Yun-Xin Chen, Yue-Hong Huang, Xiao-Zhong Wang, Department of Gastroenterology, Union Hospital of Fujian Medical University, Fuzhou 350001, Fujian Province, China;Expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 in hepatic stellate cells during rat hepatic fibrosis and its intervention by IL-10[J];World Journal of Gastroenterology;2005-12
7 Yang Cheng, Institute of Liver Disease, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China Pierre Desreumaux, Sevice des Maladies de I'Appareil Digestif et de la Nutrition, H(?)pital Huriez, CHU Lille 59037, France;5-aminosalicylicacid is an attractive candidate agent for chemoprevention of colon cancer in patients with inflammatory bowel disease[J];World Journal of Gastroenterology;2005-03
8 Li-Juan Zhang Jie-Ping Yu Department of Gastroenterology,Renmin Hospital,Wuhan University Medical School,Wuhan 430060,Hubei Province,China Dan Li Yue-Hong Huang Zhi-Xin Chert Xiao-Zhong Wang Department of Gastroenterology,Union Hospital of Fujian Medical University,Fuzhou 350001,Fujian Province,China;Effects of cytokines on carbon tetrachloride-induced hepatic fibrogenesis in rats[J];World Journal of Gastroenterology;2004-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved