Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Difficult and Complicated Cases》 2017-04
Add to Favorite Get Latest Update

Protective effects of diammonium glycyrrhizinate on peritoneal dialysis rat model of peritoneal function

WEI Zhifeng;LU Jifang;LIU Shengjun;LI Sumin;WNAG Linlin;LIU Hua;Department of Nephrology,First Affiliated Hospital of Hebei North University;  
Objective To study the protective effects of diammonium glycyrrhizinate on the peritoneal function of peritoneal dialysis rats.Methods Forty male rats were randomly divided into five groups,namely control group,model group,saline group,pentoxifylline group,glycyrrhizin diamine group,10 rats in each group,continuous experiment for 4 weeks,the peritoneal function in rats after 4 weeks(ultrafiltration,Durea/Purea) and related indexes(blood urea nitrogen creatinine clearance rate,TNF-α,and MCP-1) were tested.Results The amount of ultrafiltration,D4/D0 of model group compared with pentoxifylline group and glycyrrhizin diamine group reduced significantly,Durea/Purea increased significantly(F =8.935,7.824,9.361,P 0.05),pentoxifylline group's ultrafiltration volume increased significantly than in the glycyrrhizinate diamine group,while Durea/Purea,D4/D0 were more lower,but the difference were not significant(F =7.363,8.923,P 0.05).Model group's urea nitrogen,creatinine clearance rate reduced significantly than pentoxifylline group and glycyrrhizin diamine group,Durea/Purea increased more significantly(F =7.824,7.911,P 0.05),pentoxifylline group urea nitrogen and creatinine clearance rate decreased more significantly compared to glycyrrhizinate diamine group,but the difference were not significant(P 0.05);compared with the model group,TNF-α,MCP-1 increased significantly compared with pentoxifylline group and glycyrrhizin diamine group(P 0.05),cyclohexanone theobromine group's MCP-1 and TNF-α were lower than Glycyrrhizin acid group,the difference were not significant(P 0.05).Conclusion 4.25%glucose peritoneal dialysis solution enables impair rat peritoneal function,glycyrrhizin acid can reduce peritoneal injury,reduce deterioration of peritoneal function.
【CateGory Index】: R692.5;R-332
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 1 Hits
1 CHENG Jinxiu;HAO Junrong;WANG Linlin;LIU Cuilan;PAN Xing;LIU Sheng-jun;LIU Hua;Department of Nephrology,the First Affiliated Hospital of Hebei Northern College;;Effects of Niaoduqing Granule on quality of life and TGF-β1/Smad signalling in chronic renal failure rats received peritoneal dialysis[J];实用医学杂志;2018-05
【Citations】
Chinese Journal Full-text Database 9 Hits
1 MA Dong-hong;LIU Yun;LV Yu- min;HUA Qiu-ju;GUO Ming-hao;Division of Nephrology,the First Affiliated Hospital of Xinxiang Medical College;;The effect of gremlin content in peritoneal dialysate effluent on peritoneal function[J];中国血液净化;2016-02
2 MO Li;DUAN Yingjie;Urinary Department of Internal Medicine,General Hospital of Mining Industry Group of Fuxin;Department of Neorology,General Hospital of Mining Industry Group of Fuxin;;Impact of Both Rosiglitazone(RGZ) and Enalapril on Peritoneal Function and Cytokines in Peritoneum of Rat Peritoneal Fibrotic Model[J];中国继续医学教育;2015-06
3 ZHANG Xiaolu;ZHANG Dan;WANG Yi;Yueyang Hospital of Chinese Medicine Integrated with Western Medicine,Shanghai University of Traditional Chinese Medicine;;The Experimental Research of Peritoneal Structure and Function Affected by Ligustrazine in the Course of Peritoneal Dialysis Rats[J];中国中西医结合肾病杂志;2014-09
4 TU Qiudi;ZHANG Xiaohui;SHOU Zhangfei;Department of Kidney Disease Center,the First Affiliated Hospital,Zhejiang University School of Medicine;;Correlation of micro-inflammatory status with peritoneal function in peritoneal dialysis patients[J];浙江医学;2014-14
5 WEI Zhifeng,LI Duo,LU Jifang,et al.Department of Urology,The First Affiliated Hospital of Hebei North College,Hebei,Zhangjiakou 075000,China;Effect of diammonium glycyrrhizinate on peritoneal fibrosis in rats receiving peritoneal dialysis[J];河北医药;2013-12
6 WANG Liya ZHANG Peng LU Xue'ai One Department of Nephrology,the Central Hospital of Tai′an City,Shandong Province,Tai′an 271000,China;Research of Endothelin-1 and Vascular endothelial growth factor in peritoneal transport function prediction[J];中国医药导报;2013-02
7 Rui Dong, Zhi-Yong Guo, Department of Nephrology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai 200433, China;Gastrointestinal symptoms in patients undergoing peritoneal dialysis: Multivariate analysis of correlated factors[J];World Journal of Gastroenterology;2010-22
8 LIU Wenhu, WANG Zhigang, LIU Guiling,et al Department of Nephrology,Affiliated Beijing Friendship Hospital of Capital Medical University, Beijing (100050);Longitudinal Study of Peritonitis on Peritoneal Function in CAPD Patients[J];中国中西医结合肾病杂志;2002-10
9 XIAO Jing,GUO Jia,JIN Yun-feng,ZHAO Zhi-hong,LIU Dong,ZHAO Zhan-zheng.Department of Nephrology,The First Affiliated Hospital of Zhengzhou University,Henan University Key Clinical Disciplines Open Laboratory,Zhengzhou 450052,China;Effects of cyclooxygenase-2 inhibitor on peritoneal function and angiogenesis in uremic peritoneal dialysis rats[J];中华肾脏病杂志;2013-06
【Co-citations】
Chinese Journal Full-text Database 4 Hits
1 WU Linghui;ZHANG Xiaoru;GUI Zhihong;LAN Lejian;XIANG Meijuan;XU Weihai;ZHOU Feiyan;Department of Nephrology,People's Hospital of Lishui City;;Effect of Ligustrazine Injection on the CA125 in Patients With Abdominal Dialysis[J];中国继续医学教育;2018-21
2 MA Dong-hong;LV Yu-min;LIU Yun;SHI Jing-jing;GUO Ming-hao;Division of Nephrology, the First Affiliated Hospital of Xinxiang Medical College;;Clinical characteristics and risk factors of peritoneal dialysis-related peritonitis[J];中国血液净化;2018-02
3 WEI Zhifeng;LU Jifang;LIU Shengjun;LI Sumin;WNAG Linlin;LIU Hua;Department of Nephrology,First Affiliated Hospital of Hebei North University;;Protective effects of diammonium glycyrrhizinate on peritoneal dialysis rat model of peritoneal function[J];疑难病杂志;2017-04
4 WU Yuchi;XU Yuan;SU Guobin;LU Zhaoyu;ZOU Chuan;HUANG Chunlin;The Second Afliliated Hospital of Guangzhou University of Chinese Medicine,Guangdong Provincial Hospital of Chinese Medicine;;Gastrointestinal Symptoms of End-Stage Renal Disease Patients and Strategies from Chinese Medicine Perspective Based on Academic Ideas of HUANG Chunlin[J];中华中医药学刊;2017-03
【Co-references】
Chinese Journal Full-text Database 5 Hits
1 JING Xin-geng;Department of Nephrology, High-tech People's Hospital of Baoji;;Clinical effect of peritoneal dialysis combined with hemodialysis in the treatment of chronic renal failure[J];临床医学研究与实践;2017-16
2 WEI Zhifeng;LU Jifang;LIU Shengjun;LI Sumin;WNAG Linlin;LIU Hua;Department of Nephrology,First Affiliated Hospital of Hebei North University;;Protective effects of diammonium glycyrrhizinate on peritoneal dialysis rat model of peritoneal function[J];疑难病杂志;2017-04
3 LI Lian-ye;ZHANG Lin-qi;QU Bin;;Nursing progress of peritoneal dialysis children with acute renal failure[J];中华护理杂志;2016-05
4 Lin Lin;Zheng Jing;Zhu Weiping;Department of Nephrology,the Fifth Affiliated Hospital,Sun Yat-Sen University;;Effect of TGF-β/Smad signal pathway mediated by integrin linked kinase in the progress of renal fibrosis[J];重庆医学;2015-28
5 ZHOU Zhu;CHEN Jin;;Cthrc1 and tgf-β1 / Smad and the research progress of abnormal fibrosis[J];实用医院临床杂志;2014-02
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 YUAN Baorong;Nephrology Department, Anyang People's Hospital No.6;;Effects of Niaoduqing Granule combined with calcium dobesilate on chronic renal failure and its effects on CTGF and BMP-7[J];药物评价研究;2018-09
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 WEI Yongguang;LIN Qin;PAN Miao;Department of Nephrology,Ningde Municipal Hospital,Fujian Medical University;;Inhibitive Effect of Rosiglitazone on TGF-β_1 and CTGF Expression in Rat of Peritoneal Dialysis-related Peritoneal Fibrosis[J];中国中西医结合肾病杂志;2014-07
2 YANG Jin-song;LI Zheng-hong;ZHANG Xu;SHENG Mei-xiao;Graduate School,Nanjing University of Chinese Medicine;Affiliated Hospital of Nanjing University of Chinese Medicine;;Effect of Astragaloside Ⅳ on Expression of High Glucose Dialysis Solution-Induced Fibrosis Cytokines in Human Peritoneal Mesothelial Cells[J];中国中医药信息杂志;2014-07
3 ZHANG Min;ZHAO Jing-li;Tianjin Medical University;First Hospital Affiliated to Tianjin Medical University;;The Research Progress of Using Chinese Medicine on Controlling Peritoneal Fibrosis[J];现代生物医学进展;2014-01
4 XIONG Fei,WANG Xiaoqin,ZHANG Yanmin,et al Department of Nephrology,Wuhan No.1 Hospital,Wuhan(430022);Effects of Shenxiong Injection on Tight Junction Between Rat Peritoneal Mesothelial Cells[J];中国中西医结合肾病杂志;2012-06
5 SHU Jing,ZHANG Xiao-lu,XU Zhen-yu,WANG Yi(Yueyang Hospital of Integrated Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China);Effect of Astragalus on Peritoneal Fibrosis in Rats with Injury of Tight Junctions[J];中国实验方剂学杂志;2012-01
6 LI Jinhui,CHE Lingyan,WANG Yu,ZHANG Yuyan,WAN Haitong,YANG Jiehong(Institute of Cerebro-Cardiovascular Diseases,Zhejiang Chinese Medicine University,Hangzhou 310053,China);Permeability of blood-brain barrier oxygen-glucose deprivation induced by tetramethylpyrazine-puerarin in vitro[J];中国中药杂志;2010-20
7 GONG Yan-mei1,2,ZENG Hong-bing1,LI Peng-fei 2,LIU Xiao-cheng 1,JIANG Yian1(1.Department of Nephrology,Tongji Hospital Affiliated with the Tongji Medical College,Huazhong University of Science and Technology Wuhan 430030,China;2.Department of Nephrology and ICU,Zhenhai Longsai Hospital of Ningbo City,Zhejiang Province,Zhenghai 315200,China);Effect and Mechanism of Pentoxifylline on Peritoneal Function[J];医药导报;2008-11
8 WANG Yi1, SHU Jing1, HU Weihua2(1. Yueyang Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai 200437; 2. Haici Hospital of Qingdao City);Effect of Huangqi Injectio on Abnormal Expression of Aquaporin-1 Caused by Glucose Lactate Peritoneal Dialysis Solution[J];中医杂志;2008-02
9 Peng Jing Yin Fei Li Yufei Gan Na Zhang Hongyuan.(Department of Pediatrics,Xiangya Hospital,Central South University,Changsha 410008,China);Protective effect and its mechanism of liguistrazine on blood brain barrier permeability induced by lipopolysaccharide in vitro[J];解剖学杂志;2007-05
10 CHEN Zhong-ping1,JIANG De-yong2,TANG Luo-sheng2,LIU E-hua1 (1.Department of Ophthalmology,the First Affiliated Hospital,Nanhua University,Hengyang,Hunan 421001,P.R.China; 2.Department of Ophthalmology,the Second Xiangya Hospital,Central South University,Changsha,Hunan 410011,P.R.China);Effects of tetramethylpyrazine on expression of vascular endothelium growth factor induced by advanced glycation end products on retinal pigment epithelium[J];中国现代医学杂志;2007-16
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved