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《Chinese Journal of Difficult and Complicated Cases》 2017-04
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Clinical and pathological analysis of pediatric genitourinary rhabdomyosarcoma

LIAO Lan;WANG Yan;YI Xiaojia;XU Hui;LIU Zijuan;ZHAO Chunmei;Department of Pathology,the Second Hospital of Kunming Medical University;  
Objective To investigate pediatric genitourinary rhabdomyosarcoma(RMS) ' s clinicopathologic features,immunophenotype,pathogenesis,imaging features,diagnosis and differential diagnosis,treatment and prognosis.Methods Review of 3 cases of pediatric genitourinary RMS patients admitted to the Second Affiliated Hospital of Kunming Medical University,analyze the clinicopathological features,immunophenotype and review of the literature.Results Three cases of pediatric genitourinary RMS were male,age 3-14 years old;location:near the testis in 1 cases,2 cases of bladder;histology:spindle cell RMS2 cases,RMSl cases of botryoid;immunophenotype:3 cases of RMS were different degrees of expression of Desmin,MyoD1,Myoglobin,a few cases the expression of Myogenin,Ki67 index was 30%-60%underwent surgical resection,radiotherapy and chemotherapy were not performed.Conclusion RMS is a rare soft tissue tumor in children,with a high degree of malignancy and poor prognosis.
【Fund】: 云南省应用基础研究项目(2012FB057)
【CateGory Index】: R737.1
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