Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Difficult and Complicated Cases》 2017-04
Add to Favorite Get Latest Update

The role of NLRP3 inflammasome in the pathogenesis of thromboangiitis obliterans

QIN Chuanzi;MA Jun;JIANG Weiliang;Department of General Surgery,Second Affiliated Hospital of Harbin Medical University;  
Thromboangiitis obliterans is the segmental occlusive inflammatory condition of arteries and veins,characterized by thrombosis and recanalization of the affected vessels.It is a non-atherosclerotic inflammatory disease affecting small and medium sized arteries and veins of upper and lower extremities.A large number of inflammatory cells infiltrations are found in the blood vessel wall and thrombus in patients with thromboangiitis obliterans.NLRP3 inflammasome activates caspase 1,induced by interleukin(IL) secretion of pro-inflammatory cytokines and take part in immune response',and it has been found in autoimmune diseases and arterial diseases.In this paper,the role of NLRP3 inflammasome in the pathogenesis of Thromboangiitis obliterans will be further described.
【CateGory Index】: R543
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved