Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Difficult and Complicated Cases》 2017-05
Add to Favorite Get Latest Update

The expression and clinical significance of serum levels of galectin 3 and brain natriuretic peptide in patients with congestive heart failure

LI Dan;HUANG Jiwei;WANG Yu;YANG Peng;Department of Cardiology,Zigong First People's Hospital,Sichuan Province;  
Objective To investigate the expression of serum galectin 3 and brain natriuretic peptide(BNP) and its diagnostic and prognostic value in heart failure.Methods Eighty six patients with heart failure treated in department of cardiology of Zigong First People's Hospital from January 2016 to October 2016 in Sichuan were selected as observation group,NYHA cardiac function grade Ⅱ to Ⅳ class,of which 28 cases of grade Ⅱ,grade Ⅲ in 26 cases,grade Ⅳ in 32 cases;also chose 42 cases of volunteers underwent health examination in our hospital as control group.The levels of galectin 3 and BNP in the two groups were measured and the diagnostic value of galectin 3 and BNP in the diagnosis and prognosis of heart failure was analyzed by echocardiography.Patients were followed up for 10 months after discharge and the heart events were observed.Results The levels of galectin 3,BNP and LVEDD in the observation group were higher than those in the control group(t/P =23.494/0.000,t/P =45.741/0.000,t/P =9.296/0.000) and the LVEF value was lower than that in the control group(t/P = 11.819/0.000).The higher the cardiac function level,the higher the corresponding level of galectin 3,BNP levels and LVEDD values,whereas the LVEF values were decreased.The levels of serum galectin 3 and BNP in patients with cardiac events were significantly higher than those without heart events(t/P = 22.655/0.000,t/P =29.301/0.000).Serum galectin 3 was more sensitive to heart failure diagnosis(95.8%vs.76.9%),and BNP was more specific in patients with heart failure(99.0%vs.62.4%).The difference was statistically significant(P 0.05).Conclusion The higher the level of serum galectin 3 and BNP,the lower the level of LVEF,which is of great clinical significance in the diagnosis and prognosis of patients with heart failure.
【CateGory Index】: R541.6
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 8 Hits
1 XU Xiao-xiao;JIA Ru-yi;WANG Tao;LIU Qiang;ZHEN Zhen;Department of Cardiology,The Fourth People’s Hospital of Jinan,Taishan Medical College;;Correlation Study of Galectin-3 and Soluble ST2 Levels in Heart Failure Diagnosis[J];中国循环杂志;2016-09
2 FENG Song;AN Jindou;LI Binglu;GE Wei;The First Affiliated Hospital of Zhengzhou University;;Variation and clinical significance of serum galectin-3 in children with chronic heart failure[J];临床儿科杂志;2016-07
3 YU Mei;LIU Zhaolong;MA Lijuan;YE Lingling;SHEN Jiancheng;GUO Hangyuan;Shaoxing Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University;Shaoxing People's Hospital;;Effects of Jiawei Shenfu Decoction on B- type Natriuretic Peptide,C- creative Protein,Tumor Necrosis Factor- α in Patients with Chronic Heart Failure of Heart Yang Deficiency Syndromes[J];中华中医药学刊;2016-03
4 MA Wei-li;XU Chang-cun;Department of Cardiology,the Central Hospital of Chaoyang City;;Serum galectin-3 level in heart failure patients with preserved ejection fraction and its clinical value[J];中国心血管病研究;2016-01
5 Mei Songtao;Departmen of ICU,the Affiliated Hospital of Luzhou Medical College;;The diagnostic value of galectin-3 in patients with chronic heart failure[J];南京医科大学学报(自然科学版);2015-09
6 ZHOU Yun;FU Yong-ping;SHA Zhen-qiu;The Affiliated Hospital of Shaoxing Liberal Art &Science College;;Correlation analysis between serum sodium,plasma BNP,serum uric acid and cardiac function of the senile heart failure patients with infections[J];中华医院感染学杂志;2015-08
7 LI Bin;LIU Jing;HUANG Hongxia;HUANG Jun;GAN Shouyi;Department of Cardiology,Center Hospital of Xianning;Department of Clinical Laboratory,Center Hospital of Xianning;;Relationship between Serum Levels of Galectin- 3 / Cys C and Ventricular Remodeling and Prognostic in Patients with Chronic Heart Failure[J];宁夏医科大学学报;2015-03
8 YAO En-hui;LI Shi-chun;WANG Hua-jun;Department of Cardiology,Union Hospital of Fujian Medical University;;Effects of Xinmailong Injection on Cardiac Function and Plasma BNP Level in the Patients with Chronic Heart Failure[J];中国全科医学;2014-27
Chinese Journal Full-text Database 7 Hits
1 TENG Mingzi;WANG Xiaoyan;Dept. of Cardiology,Wuxi Third People's Hospital;;Clinical Observation of Xinmailong Injection Combined with Trimetazidine in the Treatment of Chronic Heart Failure of Coronary Heart Disease (Qi Yang-deficiency)[J];中国药房;2017-26
2 LI Xinli;ZHENG Xuhui;Department of Cardiology,the First Affiliated Hospital of Nanjing Medical University;;Heart failure biomarkers:the current status in China[J];临床心血管病杂志;2017-09
3 ZONG Bin;Department of Cardiology, Xuzhou Central Hospital Jiangsu Province;;Clinical value analysis of peripheral blood sST2 on risk stratification and prognosis in patients with AHF[J];中国医药导报;2017-26
4 WU Zengfan;CHEN Weiwei;LIU Xianxia;Internal Medicine-Cardiovascular Department,The Second Affiliated Hospital of Hainan Medical University;;Effect of Xinmailong Injection on Heart Failure of Coronary Heart Disease Patients' Serum BNP,hsCRP and VEGF[J];中华中医药学刊;2017-09
5 YUAN Xue;Department of Clinical Laboratory,the First Affiliated Hospital of Chengdu Medcial College;;The expression level of serum galectin-3 and heart fatty acid binding protein in patients with chronic heart failure and its diagnostic and prognostic value[J];中国医学前沿杂志(电子版);2017-08
6 CHEN Shi-jun;HUANG Da-hai;Department of Emergency, the Second Affiliated Hospital of Hainan Medical University;;Analysis of specificity and sensitivity of changes in BNP and TNF-α levels for early diagnosis of heart failure with pulmonary infection[J];海南医学;2017-13
7 TIAN Long;The People's Hospital of Heyang County;;Effect of Buqi Changluo Recipe for Patients with Heart Failure Rooted from Coronary Heart Disease on BNP,APN,MMP-9 and It's Clinical Curative Effect Analysis[J];四川中医;2017-06
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Mei Songtao;Departmen of ICU,the Affiliated Hospital of Luzhou Medical College;;The diagnostic value of galectin-3 in patients with chronic heart failure[J];南京医科大学学报(自然科学版);2015-09
2 QIN Yue;ZHONG Lin;YANG Jun;Binzhou Medical College;;Relationship Between Blood Level of Galectin-3 and the Severity of Coronary Lesions in Patients With Coronary Artery Disease[J];中国循环杂志;2015-05
3 ZHANG Rong-cheng;ZHANG Yu-hui;ZHANG Jian;HUANG Yan;GUO Xiao;WANG Yun-hong;AN Tao;ZHOU Qiong;ZHAO Xue-mei;Liu Ni-ni;LV Rong;JI Shi-ming;Heart Failure Center,Cardiovascular Institute and Fu Wai Hospital,CAMS and PUMC;;Preliminary Research of Cardiovascular Events Risk Assessment in Patients With Advanced Heart Failure by Dynamic Changes of Three Biomarkers[J];中国循环杂志;2015-05
4 SHI Bing;YIN Qi-usheng;DONG Lan;ZHANG Jian;Department of Geriatric Cardiology,Beijing Military General Hospital;;Expression of plasma Galectin-3 in patients with post-myocardial infarction heart failure[J];中国临床保健杂志;2015-01
5 GUO Yongjun;GUAN Yongdong;CHEN Jun;KONG Yuanyuan;DENG Suzhen;QIU Min;CHEN Jiewen;Department of Emergency,the People's Hospital of Qingyuan City in Guangdong Province;;The changes and significance of soluble ST2 receptor in heart failure patients[J];中国现代医生;2014-32
6 ZHANG Qi;WU Di;FAN Yu-dong;Heart Center,Meitan General Hospital;;Clinical significance of tissue Doppler E/E' ratio and B-type natriuretic peptide in diastolic heart failure[J];中国心血管病研究;2014-10
7 YANG Xing;WEI Xue-biao;LIN Yao-wang;CHEN Wan-wen;FU Ming;ZHOU Ying-ling;CHEN Zhu-jun;WU Ying;YU Dan-qing;Guangdong Cardiovascular Institute, Guangdong General Hospital;;The diagnostic value of left atrial volume index for heart failure with preserved ejection fraction[J];实用医学杂志;2014-07
8 GAO Chao,LIU Song,LIf engtian,ZHOU Ya,LI Hui (Department of Cardiology,The Affiliated Hospital of Qingdao University Medical College Qingdao 266003,China);SERUM FIBROSIS INDEX IN THE DIAGNOSIS OF HEART FAILURE WITH NORMAL LEFT VENTRICULAR EJECTION FRACTION[J];青岛大学医学院学报;2013-05
9 GUO Mei-zhu;YAN Shi-yun;HUANG Guo-yi;Baoshan Hospital of Integrated Traditional Chinese and Western Medicine;;Research Advance on Mechanism of Traditional Chinese Medicine in Treatment of Chronic Heart Failure[J];中国全科医学;2013-36
10 Yan Yan;Department of Cardiology,FuShun Kuangwuju Zong YiYuan;;CLINICAL CHARACTERISTICS OF 114 PATIENTS WITH CHRONIC CARDIAC FAILURE[J];中国煤炭工业医学杂志;2013-09
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved