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《Chinese Journal of Difficult and Complicated Cases》 2017-05
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Effect of salbutamol sulfate and budesonide micro-pump inhalation on infantile asthma and its effects on serum levels of IL-1β and IL-12

XU Muzhen;CHEN Feng;PAN Rui;NIE Yujun;Department of Pediatrics,Xiangyang Central Hospital Affiliated to Hubei University of Arts;  
Objective To investigate the efficacy of salbutamol sulfate and budesonide micro-pump inhalation on infantile asthma and its effects on serum levels of IL-1β and IL-12.Methods 132 infants with asthma were enrolled in the Department of Pediatrics of Xiangyang Central Hospital Affiliated to Hubei University of Arts and Sciences from January 2014 to January 2016,were randomly assigned into two groups according to their order of admission,each 66 example.The control group was treated with routine asthma(anti-infection,cough and phlegm,aminophylline,dexaroethasone,etc.),the study group of children in the control group based on the treatment of children with salbutamol sulfate solution + budesonide suspension Micro-pump inhalation therapy,compared the two groups of children with the clinical curative effect,the disappearance time of symptoms and the levels of serum IL-1β and IL-12 before and after treatment.Results The total effective rate in the study group was 100.0%,the total effective rate in the control group was 89.4%,the total effective rate in the study group was better than that in the control group(x~2=6.235,P 0.05).The serum levels of IL-1β and IL-12 in the two groups were significantly lower than those before treatment(P 0.05),and the serum IL-1β and IL-12 in study group were significantly lower than control group(t =4.865,t = 5.894,P 0.05).Conclusion The use of budesonide and salbutamol sulfate solution inhalation of micro-pump in children with infant asthma,can improve the clinical treatment of children,help to relieve symptoms in children,improve the patients symptoms,and can reduce the serum IL-1β and IL-12 level,worthy of clinical application.
【CateGory Index】: R725.6
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【References】
Chinese Journal Full-text Database 2 Hits
1 LIU Na;YUAN Nianfang;KE Jinping;Dept.of Infectious Disease,Daye People's Hospital;Dept.of Gynecology,Daye People's Hospital;;Efficacy of Salbutamol Sulphate Combined with Inhalation of Budesonide Suspension in Treatment of Asthma and Effects on Respiratory Symptoms[J];中国医院用药评价与分析;2018-07
2 YANG Min;LI Linrui;MENG Yanni;CHEN Yanping;Department of Respiratory Immunology,Hunan Children 's Hospital;;Effects of budesonide on T lymphocyte subsets and related cytokines in children with bronchial asthma[J];疑难病杂志;2018-03
【Citations】
Chinese Journal Full-text Database 7 Hits
1 LV Yanqing;ZHAN Ping;GU Hongmei;LIU Faying;WANG Bangyun;Department of Pediatrics,Western District Hospital of Chengdu;;Changes in cellular immune and inflammatory factors of children with bronchial asthma in treatment with bronchovaxom capsule[J];疑难病杂志;2016-11
2 MA Chao;REN Shao-min;Department of Pediatrics,the Affiliated Hospital of Inner Mongolia Medical University;;Change and Clinical Significance of Umbilical Cord Blood Inflammatory Cytokines Levels in Neonates with Asthma[J];实用心脑肺血管病杂志;2016-09
3 CHEN Chang-xiu;CHEN Chang-feng;LIU Yan-xia;CHEN Xiao-jie;WANG Yang;SHEN Zhi-gang;WANG Shi;Department of Pediatrics,the 97th Hospital of Chinese People' s Liberation Army;;Clinical Effect of Zafirlukast on Infantile Asthma and the Impact on Serum Cysteinyl Leukotriene Level and mRNA Expression of 5-lipoxygenase-activating Protein[J];实用心脑肺血管病杂志;2016-06
4 CHENG Yanwen;DU Xinge;WANG Yingnan;SU Jian;ZHANG Jiaqi;Department of Respiratory and Critical Care Medicine,People's Hospital of Yichang City;;The protective effect of budesonide cardiac function of pneumonia with respiratory distress syndrome[J];疑难病杂志;2016-04
5 WANG Xinhua;HAN Shuguang;LV Lei;ZHAO Hongqing;Department of Respiration,Wuxi Second People's Hospital Affiliated to Nanjing Medical University;;The impact of montelukast combined with Ketotifen on the levels of serum TGF-β_1,MCP-1,SDF-1 in asthma sufferers[J];疑难病杂志;2016-03
6 LIU Xin;People's Hospital of Daqing City;;Effect of Different Approach of Atomizing Inhalation in Treatment of Asthma in Children[J];中国卫生标准管理;2016-05
7 LI Ran;ZHANG Jie;QIAO San-fu;Department of Pediatrics,Chengde County Hospital;Department of Geriatrics,Chengde Central Hospital;;The impact of combined aerosol inhalation of budesonide and salbutamol on the levels of IL-17 and IL-25 in children with acute asthma[J];临床和实验医学杂志;2015-04
【Co-citations】
Chinese Journal Full-text Database 5 Hits
1 MU Dan;ZHAO Feng;FENG Xiao-qiang;Department of Pediatrics,Affiliated Hospital of Yan'an University;;Misdiagnosis and Missed Diagnosis Analysis of 5 Children with Atypical Bronchial Asthma[J];临床误诊误治;2018-05
2 SHI Jin;Department of Pediatrics, Huangshi City Maternal and Child Health Care Hospital of East Hubei Medical Group;;Analysis of Clinical Efficacy and Safety of Montelukast Sodium in the Treatment of Children With Asthma[J];中国继续医学教育;2018-13
3 LIN Min;XIONG Hua-lan;Department of Pediatrics,People's Hospital of Guang'an District;Department of B Ultrasound Office,Guang'an District Maternal and Child Health Care Center for Family Planning;;Effect and Influence of PCT and CRP Levels of Aerosol Inhalation of Interferon and Salbutamol in the Treatment of Children with Severe Pneumonia[J];标记免疫分析与临床;2018-04
4 YANG Min;LI Linrui;MENG Yanni;CHEN Yanping;Department of Respiratory Immunology,Hunan Children 's Hospital;;Effects of budesonide on T lymphocyte subsets and related cytokines in children with bronchial asthma[J];疑难病杂志;2018-03
5 LIU Zhiwen;;Efficacy of aerosol inhalation of budesonide combined with salbutamol in treatment of bronchial asthma and its influence on pulmonary function[J];中国医学工程;2018-03
【Co-references】
Chinese Journal Full-text Database 8 Hits
1 Huang Dijia;Bao Yongjian;Chen Lin;Department of Respiratory Medicine,Guangxi Zhuang Autonomous Region Jiangbin Hospital;;The effect of combined ambroxol and ventolin treatment on the serum IL-4 and ECP levels in asthmatic patients[J];中华保健医学杂志;2017-06
2 WANG Feng;LAN Li;QIAO Yan-mei;Department of Paediatrics, Shenmu City Hospital;Department of Paediatrics, the Second Affiliated Hospital of Military Medical University, Tangdu Hospital;;Clinical observation of salbutamol sulfate combined with aminophylline in treatment of children with asthma[J];现代药物与临床;2017-09
3 Zou Juxiang;Department of Pharmacy Mianyang Central Hospital;;The effect of budesonide reduces the levels of IL-8 and CRP:the quality of life in patients with acute aggravation of chronic obstructive pulmonary disease[J];中华保健医学杂志;2017-04
4 QIN Biyuan;ZENG Chunfang;WANG Xiao;ZENG Jianming;FENG Yinhe;Department of Respiratory Medicine,Deyang People's Hospital of Sichuan Province;;Effects of ipratropium bromide in treatment of chronic obstructive pulmonary asthma syndrome and its effect on sputum VEGF,ICAM-1,IL-13 and IL-17[J];疑难病杂志;2017-09
5 Lv Rui-zhu;Department of Pediatrics,Dongming County TCM Hospital,Shandong Province;;Clinical Study of Medication Combined with Aerosol Inhalation in the Treatment of Children Bronchial Asthma[J];中国医药导刊;2017-07
6 WANG Shao-bing;HUANG Dan;WU Bin;Affiliated Hospital of Guangdong Medical University;;The Feasibility of Detecting IL-1β,IL-2 and IL-10 in EBC of Asthma Patients and Its Correlation with Disease Severity[J];中国医学创新;2017-19
7 WEN Bo;WANG Cheng-lin;LUO Li;FENG Yang;Ya'an People's Hospital;;Clinical significance of abnormal expressions of T and B lymphocytes in children with bronchial asthma[J];中国妇幼健康研究;2017-06
8 WANG Ping;Department of Rheumatism,the First People's Hospital of Hefei;;Clinical Effect and Safety of Aerosol Inhalation of Albuterol Combined with Budesonide in Treating Elderly Patients with Acute Attack of Bronchial Asthma[J];实用心脑肺血管病杂志;2017-05
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 Zhao Qianyi;Yan Yongbin;Department of Paediatrics,the First Affiliated of Henan University of TCM;;Intervention effect of Yiqi Bushen Zhichuan decoction combined with traditional western medicine on asthma in Children[J];陕西中医;2018-06
【Secondary Citations】
Chinese Journal Full-text Database 9 Hits
1 HAO Li-xiao;Department of Neonatology,the Affiliated Hospital of Yan’an University;;Clinical research of Broncho-Vaxom combined with corticosteroids and leukotriene modifier in the treatment of children with asthma[J];临床肺科杂志;2016-04
2 LIU Lin-lin;YANG Qiao-yu;HE Qing;Department of Respiratory Medicine,Renmin Hospital of Wuhan University;;Medication of Patients With Totally Controlled Asthma and Its Effect on Acute Episoded Asthma[J];中国全科医学;2015-31
3 ZHENG Juan;The First People's Hospital of Chongqing Northern New District;;Comparative Study for Clinical Effect on Bronchial Asthma between Single-dose Inhalation of Salmeterol and Fluticas and Double-dose Inhalation of Flonase[J];实用心脑肺血管病杂志;2015-10
4 LI Jun;XI Ju-yun;Department of Emergency,the 92ed Hospital of Chinese People's Liberation Army;;Comparative Study for Clinical Effect on Severe Pneumonia between Prone-position and Supine-position Mechanical Ventilation[J];实用心脑肺血管病杂志;2015-10
5 Sha Li;Shao Mingjun;Liu Chuanhe;Li Shuo;Li Zhiying;Luo Yanqing;Wang Qiang;Xu Chunyu;Zhao Jing;Ma Yu;Xu Dongqun;Chen Yuzhi;Capital Institute of Pediatrics,Centre for Asthma Prevention and Education;;The prevalence of asthma in children:a comparison between the year of 2010 and 2000 in urban China[J];中华结核和呼吸杂志;2015-09
6 ZHOU Hui-dong;Department of Respiratory Medicine,the Seventh Hospital of Shenzhen;;Clinical Effect of Ketotifen Combined with Seretide on Asthma Complicated with Allergic Rhinitis[J];实用心脑肺血管病杂志;2015-07
7 BAI Jun- lin;CHEN Pei;Department of Medicine,Hengshan County Redcross Hospital;Department of Respiratory Medicine,Xijing Hospital of the Fourth Military Medical University;;Changes and Clinical Significance of IL-16,MCP-1 Levels of Bronchial Asthma Patients[J];医学综述;2015-14
8 SHANG Shuqin;LIU Chunsheng;ZHANG Jian;FAN Xiuyu;YANG Liwei;ZHANG Li;WANG Xinliang;Department of Pediatric,Hebei Central Energy Xingtai Mining Group General Hospital;;Clinical effect and safety of small dose dopamine combine dobutamine auxiliary for treatment of children with severe pneumonia[J];疑难病杂志;2015-07
9 CHEN Xiao-Jian;ZHANG Yue-Hua;WANG Dan-Hong;LIU Yu-Ling;Department of Pediatrics,Haikou City People's Hospital;;Effects of body mass index and serum inflammatory cytokines on asthma control in children with asthma[J];中国当代儿科杂志;2015-07
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