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The research progress of chronic heart failure with ventricular arrhythmia of Shensongyangxin capsule

NIU Manman;YAN Kuipo;SUN Yanqin;ZHU Cuiling;Department of Cardiology,Henan University of Traditional Chinese Medicine;  
There are various reasons lead to heart failure,ventricular arrhythmia are more common,.CHF concurrent ventricular arrhythmia(VA) is the main cause of cardiac sudden death(SCD).Though the classical drus for CHF combined VA are Ⅱ anti-arrhythmic beta-blockers and Ⅲ anti-arrhythmic drug such as amiodarone.However,all the anti-arrhythmic drugs have lead to arrhythmia.And the Shensongyangxin capsule has the characteristic of traditional Chinese medicine,play for the treatment of chronic heart failure with ventricular arrhythmia through various mechanism,such as,the myocardial cells of ion channel,the Kv 1.4 delta N channel inhibition of peak current and regulate cardiac autonomic nervous system,increase the myocardial tissue Na~+-K~+ atpase activity and inhibition of myocardial remodeling,improvement the action such as cardiac conduction function etal.The paper reviews there search progress of Chronic heart failure with ventricular arrhythmia of Shensongyangxin capsules.
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