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Chemical Contituents of Coleus forskohlii

YAN Huan1,2,PAN Li-Li2,ZHAO Qing1,LIU Hai-Yang2(1.Yunnan University of TCM,Kunming Yunnan 650500;2.State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650204)  
Objective:To study the chemical constituents of coleus forskohlii.Methods:The chemical constituents were isolated and purified using column chromatographies and the structures were elucidated on the basis of spectra analysis.Results:Seven compounds were isolated from C.forskohlii including three phenols,two diterpenoids,and one triterpenoid saponin.The seven compounds were identified as rosmarinic acid(1),oresbiusin A(2),(E)-ferulic acid 4-O-β-D-glucoside(3),2α,3β,19β,23-tetrahydroxyolean-12-en-28-O-β-D-glucoside(4),isoforskolin(5),1,6-diacetoxy-9-deoxyforskolin(6),and β-sitosterol(7).Conclusion:Compounds 1-4 were isolated from this plant for the first time.
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