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《Drug Stanoaros of China》 2000-01
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DETERMINATION OF THE CONTENT OF CIPROFLOXACIN LACTATE INJECTION BY RP-HPLC

Zhong Yulian, Yang Ying, Liu Lifang and Zhao Xuemei (Guang zhou City Institute of Drug Control 510160)  
Objective: To establish a method for determination of the content of ciprofloxacin lactate injections. Method: Using RP-HPLC with purospher RP-18 as column, 0.025mol/L phosphoric acid (adjused the solution with triethy lamine to PH3.0)-acetonitrile(87: 13)as the mobile phase. Detection wavelength was 278nm. Results: The linear correlation was observed is the range 4-130ug/ml (r=1.0000).The average recovery was 99.3%, RSD=0.8% (n=6). Conclusion: The method is simple, quick and specific.
【CateGory Index】: R927
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【References】
Chinese Journal Full-text Database 1 Hits
1 Gao Jing Wang Tao Department of Pharmacy, affiliated Hospital of Xuzhou Medical College Xuzhou, Jiangsu 221002, China;Study on the Compatible Stability of Lactic acid ciprofloxacin Injection with Metronidazole Injection by RP-HPLC[J];Chinese Medicine Modern Distance Education of China;2009-12
【Co-references】
Chinese Journal Full-text Database 3 Hits
1 LIU Xiao-hui (The Affiliated Hospital Anhui University, Hefei 230039,China);The COMPATIBLE STABILITY BETWEEN CIPROFLOXACIN AND CEPHRADINE[J];West China Journal of Pharmaceutcal Sciences;2001-03
2 ZHANG Jian, TAN Yuan Liang\+1, CHEN Dong Hua, YUAN Yu Hong, TANG Wan Jun, HU Xiao An Department of Chemistry, South Central College for Nationalities, Wuhan 430074; \+1Wuhan Garrison Command Pharmaceutical Factory, Wuhan 430022;Application of Thermogravimetry to the Study of Thermal Decom-position Kinetics of Metronidazolum and Its Deter-mination[J];JOURNAL OF CHINA PHARMACEUTICAL UNIVERSITY;2000-04
3 CHEN Xian-mei,ZHENG Li-jie(Zhejiang Jianfeng Pharmaceutical Holdings,Jinhua 321016,China);Determination of ciprofloxacin lactate eye drops by HPLC[J];Chinese Journal of Modern Applied Pharmacy;2006-S2
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 LIU Na,SUN Han-wen,HE Pan(Key Laboratory of Analytical Science and Technology of Hebei Province,College of Chemistry and Environmental Sciences,Hebei University,Baoding 071002,China);Determination of Ciprofloxacin Injection by Capillary Electrophoresis[J];Journal of Hebei University(Natural Science Edition);2010-01
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