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《Chinese Journal of Pharmaco Epidemiology》 1994-01
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The Influence on White Blood Cell by Psychotropic Drug in 856 Patients

Zeng zhaoxiang, Liu Lin, Li Zhicheng, Liu Yongying, Zhang Zhaocai Jining Mental Hospital, Shandong (272151)  
Authors analysed the change of WBC during psychotropic therapy in 856 patients. we found that 11. 1% of all patients appeared leukocytosis, 3. 6% was leukocytopenia, 0.2% was agranulocy-tosis. In all leukocytopenia, the influence by clozepine, clorpromazine and sulpiride were serious, especially by clozepine. The leukocytopenia patients would have died in short time if it was not rescued promptly when agranulocytosis had appeared. It is necessary to examine WBC count and classification regularly in patients by psychotropics therapy.
【CateGory Index】: R595.3
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