Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《药学进展》 1997-01
Add to Favorite Get Latest Update

Antisense Oligonucleotides Drug Phosphorothioate Oligonucleotides

Liu Hong Wei Dongzhi Institute of Biochemistry, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237  
Phosphorothioate oligonucleotides(PS ODN) are regarded as prospective pharmaceuticals. The latest research progress about the synthesis technique, antisense properties, action principle and pharmacokinetics of PS ODN were discussed in this paper.
【Fund】: 国家自然科学基金
【CateGory Index】: R969.1
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 3 Hits
1 TENG Da cai, XU Tie jun, ZHANG Feng zhen (Department of Human Anatomy, Xuzhou Medical College, Jiangsu Xuzhou 221002 China);The Antisense Oligodeoxynucleotide Technique and Its Use in the Research on N-methyl-D-aspartate Receptor Subunits[J];Progress of Anatomical Sciences;2004-03
2 LIN LI; YUAN WEN-JUN; CHU AIAO-LING;XU HONG; LI LING; REN AN-JING(Department of Physiology, Second Military Medical University, Shanghai 200433;Department of Physiology, Fuzhou Senior Medical School of PLA, Fuzhou 350003);PREVENTIVE EFFECT OF ENDOTHELIN-1 mRNA ANTISENSE OLIGONUCLEOTIDE ON ACUTE MYOCARDIAL ISCHEMIC ARRHYTHMIA IN RATS[J];ACTA PHYSIOLOGICA SINICA;1999-05
3 CHEN Yongxiong, YU Xueqing, SUN Yuling, et al. (Department of Nephrology, First Affiliated Hospital, Sun Yat-sen University of Medical Sciences, Guangzhou 510080, China);Expression regulation of osteopontin by its antisense oligonucleotides in renal epithelial cells of interstitial nephritis[J];Chinese Journal of Nephrology;2000-05
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Tang Jian et al( Lab of Cardiopulmonary Endocrinology,Beijing Medical University. Beijing );The Effect of Endothelin on The Cardiovascular Function in Rats[J];;1989-03
2 Zeng Qiang, Li Zhenjia, Yu Xiajun, Zhang Linxiang, Yuan Jun, Fan Yingxian. General Hospital of PLA, Beijing;RADIOIMMUNOASSAY OF ENDOTHELIN[J];Medical Journal of Chinese People's Liberation Army;1991-06
3 CHEN Su-Hong, LU Dan-Dan, ZHANG Wei, WANG Sheng-Qi* (Institute of Radiation Medicine, Academy of Military Medical Scien ces, Beijing 100850, China);Sequence confirmation of phosphorothioate antisense oligodeoxynucleot ides using direct Sanger sequencing reactions[J];Bulletin of The Academy of Military(Medical Sciences);2004-05
4 WANG Shengqi, LIN Li, CHEN Zhongbin, LIN Ruxian, CHEN Suhong, GUAN Wei & WANG XiaohongBeijing Institution of Radiation Medicine, Beijing 100850, China;Effect of antisense oligonucleotides targeting telomerase catalytic subunit on tumor cell proliferation in vitro[J];科学通报(英文版);2002-12
5 ZHANG ZHAO; LI YU-LONG; HE RUI-RONG(Department of Physiology,Institute of Basic Medicine,Hebei Medical University,Shijiazhuang 050017);EFFECTS OF ENDOTHELIN ON ELECTROPHYSIOLOGICAL AND CONTRACTILE ACTIVITY OF GUINEA PIG PAPILLARY MUSCLES[J];ACTA PHYSIOLOGICA SINICA;1997-02
6 TANG Zong-Xiang;LI Bao-Ming;BAO Yong-De(Shanghai Institute of Physiology,Chinese Academy of Sciences,Shanghai 200031);Antisense oligonucleotides:new tools for physiological study[J];CHINESE BULLETIN OF LIFE SCIENCES;1999-04
7 YANG Binghu, SUN Oujun, ZHANG Minli, WANG Shengqi (Beijing Institute of Radiation Medicine, Beijing 100850, China);Determination of Antisense Phosphorothioate Oligonucleotide Drug Cantide by Capillary Gel Electrophoresis[J];Chinese Journal of Chromatography;2004-03
8 YANG Ying,DU Qing-you,WANG Sheng-qi. Beijing Institution of Radiation Medicine,Beijing 100850,China;Synergism of an antisense oligodeoxynucleotides targeted to hTERT in combination with chemotherapeutic drugs on inhibiting the proliferation of HepG2 cells[J];Chinese Journal of Hepatology;2003-12
9 Yu Xueqing, Chen Weiying, Shen Qingrui, et al. Department of Nephrology, The First Affiliated Hospital, Sun Yatsen University of Medical Sciences, Guangzhou 510080;CD44 and its ligand osteopontin expression in the development of rat antiGBM glomerulonephritis[J];CHINESE JOURNAL OF NEPHROLOGY;1998-02
10 WU Jie,LIU Ke-liang (Beijing Institute of Pharmacology and Toxicology,Beijing 100850,China);The advances in research of delivery system for antisense oligonucleotides[J];Chinese New Drugs Journal;2003-05
【Secondary References】
Chinese Journal Full-text Database 3 Hits
1 LIN Li, YUAN Wen Jun (Department of Physiology, Second Military Medical University, Shanghai 200433, China);Endothelin-1-a proarrhythmogenic mediator[J];Journal of Beijing Medical University;2001-04
2 PAN Yan-Xia 1,2, LIN Li 1, YUAN Wen-Jun 1,*, WU Guo-Hong 1, TANG Chao-Shu 3 1Department of Physiology, Second Military Medical University, Shanghai 200433; 2Department of Physiology, Fujian Medical University, Fuzhou 350004; 3Department of Physiology and Pathophysiology, Health Sciences Center, Peking University, Beijing 100083;Preventive effect of endothelin-1 pretreatment on hypoxia-induced injury in cultured neonatal rat cardiomyocytes[J];Acta Physiological Sinica;2003-02
3 CHEN Honghui, ZHANG Mingliang, YANG Xuefeng, FENG Yingjuan, YAN YueqingDepartment of Digestion, 2nd Affiliated Hospital, Nanhua University Nanhua University 421001,China;Expression of osteopontin in the alcoholic hepatic fibrosis[J];Chinese Journal of Gastroenterology and Hepatology;2005-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved