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The Change in the Myocardial Enzyme Spectrum,Renal Function and Electrolytes of Neonatal HIE and Its Clinical Signifi-cance

DAI Hongqing. Department of Paediatrics , The People' s Hospital of Wugang City, Hunan Province 422400  
Objective: To detect myocardial enzyme spectrum, renal function and electrolytes of the moderate and severe neonatal hypoxic-ischemic encephalopathy (HIE) and analyse the clinical significance. Method: Myocardial enzyme spectrum (AST, LDH, CK, CK-MB, HBDE), renal function (BUN, Cr), and serum electrolytes (Na+、 K+、 Cl-、 Ca2+、 Mg2+ ) of 40 neonates with moderate and severe asphyxia were detected in acute and recovery phases and compared with normal ones. Result: Items of the myocardial enzyme spectrum of the moderate and severe asphyxia neonates had a higher level than that of the control group and the difference was obvious (P 0.01), So is the renal function. But the level of the serum Ca2+ , Mg2+ is obviously lower than the control group. Conclusion: Besides brain damage, disfunctions of the heart and kidney occur also in HIE, therefore , detecting the myocardial and renal functions and prompt treatment are very important to decrease the incidence of the sequela and increase survival rate.
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