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Clinicopathologic and Immunohistochemical Analysis of Paraganglioma

QIAN Jianjun,GU Xuewen,WANG Zhengbing,et al.Department of Surgery,Subei People's Hospital of Jiangsu 225001  
Objective:To investigate the characterization of clinic op athology and immunohistochemistry of paraganglioma Methods:Immunoh i stochemistry was used to examine the NSE,CgA,Sy,S-100,GFAP,CK,EMA and Vim exp ression in 21 cases of paraganglioma Results:Histopathological feat u res with paraganglioma were similar to those of the neuroendocrine neoplasm.The p ositive rates of NSE,CgA,Sy,S-100,GFAP were 100%,76 2%,80 9%,71 4%and 71 4%,CK?EMA and Vim were negative.Conclusion:Histopatholoical features are not the differential diagnosis index between benign and malignant p araganglioma.Benign and malignant paraganglioma is relating the biological beha vior.Expression of immunohistochemistry provides the basis for differential diag nosis and prognosis in paraganglioma.
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