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《The Journal of Medical Theory and Practice》 2005-01
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Observation of the Effect Of L-carnitine in the Treatment of Hemodialysis Patients with EPO-resistance

YANG Ming.The People's Hospital of Lianzhou,Guangdong Province 513400  
Objective: To observe the effect of L-carnitine in the treatment of the hemodialysis patients with erythropoietin(EPO)-resistance.Methods: 48 patients with EPO-resistance were randomly divided into 2 groups.L-carnitine 1.0g intravenously infuse after every dialysis session in therapy group(n26),and the control group(n22) warit given L-camitine,but saline 5ml. All of the patients were observed 8 weeks.Results:Hemoglobin(Hb)and hematocrit (Hct) were significantly higher in therapy group than that in control group(P0.01).After 5weeks,the dosage of EPO in therapy group reduced 36%than before,but without change in control group.Conclusion: L-carnitine can significantly improve EPO-resistance of hemodialysis patients,and correct anemia.
【CateGory Index】: R459.5
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