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The Clinical Significance of CRP in COPD Patients of Acute Aggravate Stage before and after Treatment

HANG Yonglun*, CAI Meizhu*, LI Duo. *Department of Laboratory, Affiliated Hospital of Luzhou Medical collage 646000  
Objective: To observe the serum C-reactive protein(CRP) levels variation in chronic obstructive pulmonary disease(COPD) patients of acute aggravate stage before treatment, after 1 and 2 weeks treatment. Methods: The serum levels of CRP were measured by nephelometry immunoassay, and compared with healthy controls.Results: The levels of serum CRP in COPD patients of acute aggravate stage before and after 1 week treatment were significantly higher than healthy controls( P 0.01 or P 0.05), after 2 weeks treatment, the levels of serum CRP approach controls. Conclusions: The serum CRP is good marker in estimating pulmonary infection degree and effect of antibiotic.
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