Effect of Early Enteral Nutrition on Cellular Immunity of Postoperative Patients with Severe Abdominal Trauma.
MIAO Dingding,LIU Shuang,YU Jun,et al. Nanshan People’s Hospital of shenzhen City,Guangdong Province.518052
Objective: To evaluate the effect of early enteral nutrition on cellular immunity of patients following surgery for severe abdominal trauma. Methods: 30 patients with severe abdominal trauma were randomly divided into two groups: enteral nutrition group (EN group) and parental nutrition group (PN group). PN group was given total parental nutrition (TPN). In the EN group, since the first post-operative day neutrinos(r) was infused, the infused volume was increasingly added from 500mL/d to 1500mL/d. Cell immune indicators such as T-cell subgroup (CD_3~+、CD_4~+、CD_8~+) and NK cell activity were measured before operation and on the 8th post-operative day. Results: The levels of CD_3~+、CD_4~+、CD_8~+ and NK cell activity were decreased in PN group after operation; In EN group the levels of CD_3~+、CD_4~+、CD_8~+ and NK cell activity did not change significantly. Conclusion: Compared with the parenteral nutrition, enteral nutrition can improve obviously the cellular immunity function in patients undergoing surgery for severe abdominal trauma.