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Evaluation of S-100 Protein in Plasm Fluid of the Patients with Acute Carbon Monoxide Poisoning

LI Fuxiong LI Weijun LIAO Changzheng, et al.Central Hospital of Longgang ,Shenzhen City,Guangdong Province 518116  
Objective:To observe plasm S-100 protein levels in patients with acute carbon monoxide poisoning and expiore its clinical significance. Methods:24 patients with acute carbon monoxide poisoning were randomly divided into three groups:group A(gentleness poisoning group),group B(moderate poisoning group)and group C(severe poisoning group).Plasma S-100 preptein levels of 24 patients and 20 cases in normal control group were detected respectively with ELISA. Results: Plasm S-100 protein level in group A was not higher than that in normal control group (P0.05); The levels of plasm S-100 protein in group B and group C were significantly higher than that in control group (P0.01),Plasm S-100 protein level in group C was obviously higher than that in group B also.There was no statistically significant difference in the plasma S-100 protein level between the patients with delayed encephalopathy and those without delayed encephalopathy (P0.05).Conclusion: Determination of plasm S-100 protein level can contribute to assessing the severe degree of acute carbon monoxide poisoning,but it can not predict the occurrence of delayed encephalopathy.
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