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Interlenkin-4 and Interlenkin-4 Receptor in Respiratory Syncytial Virus Pneumonia in Infants and Young Children in Correlation Research

HU Chunmei.Department of Pediatrics,The Sixth People's Hospital of Shenzhen City,Guangdong Province 518052  
Objective:Interlenkin-4 and interlenkin-4 receptor in respiratory syncytial virus pneumonia in infants and young children in correlation research.Methods:Totally 45 children who were hospitalized for pneumonia for RSV were recruited in this study,a group of 51 healthy children were selected as contrast.The total IL-4 and IL-4R concertrations in serum samples were measured by Enzyme linked immunosorbent assay(ELISA).Results:(1) In RSV pneumonia group and In control group,level of serum IL-4 were(294.68±90.65) ng/L,(146.75±37.26)ng/L(P0.01).(2)In RSV pneumonia group and In control group,level of serum IL-4R were(17.60±13.80)μg/L,(7.47±4.29)μg/L.Respectively,the diffrence was significant between the two groups(P0.01).Conclusion:Level of serum IL-4 and IL-4R were increased significantly in RSV pneumonia,with progess of the disease increased concentration,indicate that the RSV pneumonia severity and IL-4 and IL-4R concents increased positive correlation.
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