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Mitomycin for Laryngeal Cancer Cell Growth

JIANG Juan.The Laishan Sorting of Yantai Yuhuangding Hospital,Shandong Province 264000  
Objective:To mitomycin C(MMC)in human laryngeal squamous cell carcinoma Hep-2 cell activity.Methods:Experimental methods in vitro cell culture,application MTT,Trypan blue staining techniques detect MMC on Hep-2 cell viability,while application of immunohistochemical detection of nm23 nm23 protein expression.Results:Hep-2 cells in the MMC under the action of cell death after 48 hours of 90%,nm23 protein in laryngeal cancer cells with MMC in the role of increased expression of continuity of time.Conclusion:Mitomycin affect human laryngeal carcinoma cells(Hep-2)growth,reducing the activity of Hep-2 cells to achieve therapeutic effect.
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