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Research on Treatment of Tanreqing Injection Combined with Antibiotics for Patients with Ventilator Associated Pneumonia(type of TanReYongFei)

CHEN Jimin;XI Yao;Department of Geriatric Medicine,Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine;  
Objective:To investigate the treatment effects of Tanreqing injection combined with antibiotics for patients with ventilator associated pneumonia(VAP)(type of TanReYongFei).Methods:96VAP patients(type of TanReYongFei)were randomly divided into two groups,experimental group of 51 cases and control group of 45 cases.The cases of control group were treated with antibiotics as well as support therapy.The cases of experimental group were treated with Tanreqing injection(20ml one day)for besides for those therapies as well.The therapy course of both groups was10 days.The result of these therapies,clinic pulmonary infection score(CPIS),acute physiology and chronic health evaluation Ⅱ(APACHEⅡ)score,days of mechanical ventilation,the rate of successful weaning for the first time,serum level of C reaction protein(CRP)and procalcitonin(PCT)were compared respectively between the two groups.Results:The efficiency of experimental group was superior to that of control group(P0.05).There were significantly differences in CPIS,days of mechanical ventilation,serum level of CRP and PCT between the two groups(P0.05).There were no significantly differences in APACHEⅡ score and he rate of successful weaning for the first time,between the two groups(P0.05).The side effect was low in both groups.Conclusion:The treatment effect of Tanreqing injection combined with antibiotics for VAP patient(type of TanReYongFei)is better than that of using antibiotics only.
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