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Clinical Study of Therapeutic Effect and Adverse Reaction of Trimetazidine in the Treatment of Coronary Heart Disease with Chronic Heart Failure

LI Hongyu;Department of General Medicine,the Traditional Chinese Medicine Hospital of Yichuan County,He’nan Province;  
Objective:To explore the clinical therapeutic effects and adverse reaction of trimetazidine in patients with coronary heart disease and chronic heart failure.Methods:65patients were randomly divided into treatment group and control group.Patients in the control group were received standardized treatment according to the guidelines,while the treatment group was treated by trimetazidine besides the therapy of control group.All the patients were given three months of treatment.During the preparation before and 3 months after treatment,the clinical symptoms,6min walk test,heart function grade of NYHA,and the examination results of heart color doppler ultrasonic diagnostic instrument were compared respectively between the two groups.Results:All the observed indices of treatment group compared with the control group there were no statistically significant difference(P0.05).Adverse reaction:1case had dizziness and gait instability,1case had neutropenia in treatment group.Conclusion:Trimetazidine has no satisfactory curative effect in the treatment of coronary heart disease with chronic heart failure.
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