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《Acta Pharmaceutica Sinica》 1986-05
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ZHANG Yin-Shen~*, CAO Guan-Kun, PENG Si-Xun, DNI De-zai and JIN Ling~(**) (Nanjing College of Pharmacy, Nanjing)  
With an attempte to search for potent nonsteroidal antiinflammatory drugs with less side-effects,twenty Six derivatives of 4-hydroxy-3-aminomethyldiphenyl and 4(2)-cyclohexyl,-2(4)-aminomethylphenol were prepared by Mannich reaction. Nineteen of the compounds were tested in rats. Some of these compounds showed significant antiinflammatory and antipyretic-analgesic activities. Antiimplanration test was also carried out on twenty of the compounds, but none was found active.
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Chinese Journal Full-text Database 6 Hits
1 Zang Yuying Chen Xingzhi;Effects of 4-hydroxy-3-(3′,5′-dimethyl piridinomethyl)-biphenyl on Cultured Heart Cells in vitro[J];;1989-03
2 Zang Yuying et al. (Dept of pharmacology Suzhou Medical College, 215007);Effects of 3-[4-2(hydroxyethyl) piperazinyl] methyl-P-dihydoxydiphenyl on Cultured Heart Cells in vitro[J];;1991-01
3 ZN Xia, GK Cao and SX Peng (Division of Medicinal Chemistry, China Pharmaceutical University, Nanjing);SYNTHESIS AND QUANTUM CHEMICAL CALCULATION OF 4-HETEROARYL-MONO/DI-AMINOMETHYLPHENOL DERIVATIVES[J];Acta Pharmaceutica Sinica;1988-08
4 Zhang Yinshen, ZhangYuyin, Peng Sixun, Dai Dezai~* Division of Medicinal Chemistry; ~*Devision of Pharmacology);SYNTHESIS OF 4-ARYL/HETERAYLAMINOMETHYL-PHENOLS[J];Journal of China Pharmaceutical University;1988-03
5 Dai Dezai, Wu Chuwu, Huang Jun Research Division of Pharmacology;Anti-inflammatory Activity of New Non-steroidal Antiinflammatory Agent: Derivatives of 4-(2-Thiophene Carbonyl)-Phenol Compounds[J];Journal of China Pharmaceutical University;1991-01
6 Huang Wen-long Yang Zhen-xiang Peng Si-xun (China Pharmaceutical University,Nanjing);STUDIES ON CALCIUM ANTAGONIST:SYNTHESIS OF DAURICINE AND BERBAMINE DERIVATIVES[J];;1987-10
Chinese Journal Full-text Database 4 Hits
1 CHEN QING-HUA LU JU-XIAN CHEN LAN-GUI ZHAO XUE-WEN (Institute of Hygiene, Chinese Academy of Medical Sciences, Beijing);THE ALKYLATION OF PHENOLIC HYDROXYL GROUP IN BERBAMINE[J];Acta Chimica Sinica;1981-03
2 Sun Cunji, Zhang Xinyi, Yang Xingzhong, Wang Pingping, Shen Jian, Shu Yun and Ji Ruyun (Kyi Zu-yoong) (Shanghai Institute of Materia Medica, Acadimia Sinica);STUDIES ON DRUGS FOR CORONARY DISEASES Ⅱ. SYNTHESIS OF COMPOUNDS RELATED TO CHANGROLIN AS POTENTIAL ANTIARRHYTHMIC DRUGS[J];Acta Pharmaceutica Sinica;1981-08
3 LI Gui-rong, FANG Da-chao, HU Chong-jia and LU-Fu-hua (Department of Pharmacology, Wuhan Medical College, Hankou);EFFECTS OF DAURICINE ON THE DOSE—EFFECT RESPONSE OF ISOPRENALINE AND Ca~(2+) AND THE ELECTRO-MECHANIC ACTIVITY IN CAT PAPILLARY MUSCLE[J];Acta Pharmaceutica Sinica;1983-09
4 KANG Ai-Li and SUN Cun-Ji (Shanghai Institute of Materia Medica, Academia Sinica, Shanghai);STUDIES ON DRUGS FOR CORONARY DISEASES. Ⅲ. SYNTHESIS OF SOME MANNICH BASES OF SUBSTITUTED AMINOPHENOLS[J];Acta Pharmaceutica Sinica;1986-12
【Secondary References】
Chinese Journal Full-text Database 6 Hits
1 Hu Zhuoyi, et al (China Pharmaceutical University, Nanjing, Jiangsu, China);BENZYLISOQUINOLINE ALKALOIDS AND THEIR ANALOGUES INHIBIT THE ACTIVITY OF PHOSPHODIESTERASE STIMULATED BY CALMODULIN[J];Acta Academiae Medicinae Xuzhou;1988-01
2 Cai Huiming, Huang Zhenya, Yang Zhenxiang, Wang Erhua and Peng Sixun(Division of Medicinal Chemistry);Q-MODEL INFORMATION CLUSTER ANALYSIS ASSISTED DESIGN OF DAURICINE DERIVATIVES[J];Journal of China Pharmaceutical University;1989-01
3 Jiang Chungang, Fan Ming, Cai Huiming~1, Sheng Longsheng Analytical and Computer Center; ~1Division of Medicinal Chemistry;Structure Study on the Dauricine and Daurisoline and Their Derivatives by Self-Chemical Ionization/Fourier Transform Mass Spectrometry[J];Journal of China Pharmaceutical University;1991-01
4 Li Yunman;Wang Qiujuan;Jiang Lili(Department of Physiology,China Pharmaceutical University,Nanjing 210009);Anti-inflammatory Effect of No.Ⅰ Feng Shi Kang[J];JOURNAL OF CHINA PHARMACEUTICAL UNIVERSITY;1995-02
5 Hou Xiaoping;Huang Wenlong;Peng Sixun(Division of Medicinal Chemistry,China Pharmaceutical University,Nanjing 210009);By-products from Mannich Reaction of Dihydrobenzopyranones[J];JOURNAL OF CHINA PHARMACEUTICAL UNIVERSITY;1996-02
6 LUO Shun de,YANG Jian,WANG Hui,CAI Hong sheng (The People Hospital of Wuhan University,Wuhan 430060,China);Studies on synthesis and antiarrhythmic quantitative structure-activity relationships of liensinine's derivatives[J];Chinese Pharmaceutical Journal;2002-09
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