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《Acta Pharmaceutica Sinica》 2008-01
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Chemical constituents from Spatholobus sinensis

YIN Ting~1,LIU Hua~1,WANG Bin~1,TU Guang-zhong~2,LIANG Hong~1,ZHAO Yu-ying~(1)(1.Department of Natural Medicines and the State Key Laboratory of Natural and Biomimetic Drug,School of Pharmaceutical Sciences,Peking University Health Science Center,Beijing 100083,China;2.Beijing Institute of Microchemistry,Beijing 100091,China)  
Spatholobus sinensis is a plant of the Spatholobus genus(Leguminosae family).Its caulis are used as "ji-xue-teng" regionally.However,to our knowledge,no phytochemical investigation on(S.sinensis) has been reported to date.In this study,eight compounds were isolated from the ethanol extract of the caulis of S.sinensis,by solvents extraction and column chromatography methods.By analysis of their physic-chemical constants and spectral data,the structures of 8 compounds were identified as spatholosineside A(1),2′,4′,5,7-tetrahydroxyisoflavone(2),isoliquiritigenin(3),lupinalbin A(4),coumestrol(5),naringenin(6),protocatechuic acid(7),leonuriside A(8).Compound 1 is a new compound.
【Fund】: 国家自然科学基金重点资助项目(20432030);; 长江学者和创新团队计划资助项目(985-2-063-112).
【CateGory Index】: R284.1
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