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《Journal of Molecular Diagnostics and Therapy》 2016-03
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Influence of group B Streptococcus(GBS)infection on pregnancy outcome

ZHAO Xiaoya;XIE Yueying;ZHOU Xuli;XIE Gang;WEN Jia;HONG Wei;Deparment of Pathology,Xiangtan City Maternal and Child Health-Care Hospital;  
Objective To investigate the group B Streptococcus(GBS)infection rate in pregnant women during late pregnancy and its influence on pregnancy outcomes. Methods A total of 4 091 women in later stages of pregnancy who had regular antenatal examinations in the Xiangtan City Maternal and Child Health- Care Hospital were chosen from Jan. 2014 to Dec. 2014. The method of real- time fluorescence quantitative polymerase chain reaction(RT- PCR)was utilized to detect with the presence of GBS. A 1∶1matching case control study was carried out with 225 pregnant women positive of GBS and 225 women negative of GBS,and the pregnancy outcomes in the 2 groups were followed up. Results The late pregnancy GBS infection ate in 4 091 pregnant women was 5.4%(225/4 091). Compared with the GBS negative group,the GBS positive group had a higher incidence of premature rupture of membranes[20.4%(46/225)vs 1.1%(25/225)],intrauterine infection [19.1%(43/225)vs 7.5%(17/225)],neonatal infection[11.5%(26/225)vs 5.7%(13/225)],the difference sare statistically significanct(P0.05). There were no statistically significant differences in the premature birth and dystocia(P0.05). Conclusions Maternal GBS carrier in late gestation are more likely to have adverse pregnancy outcomes due to increased incidences of intrauterine infection,premature rupture of membranes and neonatal infections. It is necessary for women in later stages of pregnancy to take routine screening of GBS infection.
【CateGory Index】: R714.251
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