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《Journal of Molecular Diagnostics and Therapy》 2018-05
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Advances in research on extracellular vesicles and erythropoiesis and related products

SUN Shipeng;AN Cheng;LIU Guijian;WU Zhikui;Clinical Laboratories,Guang'anmen Hospital,China Academy of Chinese Medical Sciences;  
Extracellular vesicles(EVs)are small phospholipid vesicles(≤1 μm in diameter)containing molecules,lipids,m RNAs and micro RNAs,including microvesicles and exosomes.EVscan transmit functional information between tissues and cells,and involve in tumor invasion,metastasis,immunity and hematopoiesis.In recent years,studies have found that EVs also play an important role in erythrocyte biology.Analysis of erythrocyte-related functional EVs is expected to provide new ideas and methods for the study of erythropoiesis,anemia and transfusion-related immune regulation.In this review,the research progress of erythropoiesis and related extracellular vesicles in erythrocyte products will be summarized,to provide new ideas for the treatment of erythrocyte diseases.
【Fund】: 国家自然科学基金青年基金(81403192);; 国家重点基础研究发展计划(973计划)(2010CB530406);; 吴阶平医学基金会临床科研专项资助基金(320.6750.18107);; 国家中医临床研究示范基地科研专项暨所级科研基金课题(2014S305)
【CateGory Index】: R392-33
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