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《China Medical Equipment》 2007-12
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Laser Doppler measurements of cochlear blood flow With the assistance of Perimed Flowmetry

Yang Jian,Liu Bo (Beijing Tongren Hospital attached the Capital Medical University,Beijing 100730,China)  
Objective Based on the structure features of rabbits bulla, find a appropriate method for the laser Doppler measurements of cochlear blood flow. Materials Methods In the present study, 10 male New-Zealand Rabbits were utilized. The animals were prepared for auditory brainstem evoked potential (ABR) and distorted product otoacoustic emission (DPOAE) before and after the measurements, proved the normal hearing function. The bulla were exposed with the anterior-auricle incision, then opened a ventral window.The laser Doppler flowmetry probe was put right on the promontory they were killed and observed the cochlear hair cells with scanning electron microscopy. Results During the operation, no significant bleeding, operation field is clear, only few levels of organization needed to be detached and less damage was done. No significant changes were found in the hearing function. Conclusion Our datas show that for the laser Doppler measurement of rabbit cochlear blood flow, it's safe to choose the preauricular incision And the results of laser Doppler of Perimed measurement was stable.
【CateGory Index】: R764
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