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《China Medical Equipment》 2018-06
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An analytical investigation of Cine PC-MRI for hydromechanics of cerebrospinal fluid of Chiari Malformation Type Ⅰ

CHENG Cheng;TAO Ben-zhang;SHANG Ai-jia;Department of Neural Tumor,China Armed Police General Hospital;  
Objective: To apply cine phase contrast-MRI(Cine PC-MRI) to assist the selection of surgical strategies for patients with Arnold-Chiari malformation type Ⅰ, and to analyze and contrast the characteristics of hydrodynamics of cerebrospinal fluid before and after surgery. Methods: 19 patients with Arnold-Chiari malformation type Ⅰ were enrolled in the research. Cine PC-MRI was used to confirm the location of circulatory disturbance of cerebrospinal fluid, and posterior fossa reconstruction or cisterna magna reconstruction were selected and applied. And the mean flow(MF), stroke volume(SV), regurgitant fraction(RF) and maximum peak velocity(V_(max))(which were divided into V_(umax) and V_(dmax)) of region of interesting(ROI) were quantitatively analyzed. And the prognosis evaluation was achieved by using Chicago Chiari Outcome Scale(CCOS). Results: Cine PC-MRI showed that MF and SV of cerebrospinal fluid of ROI post operation increased, and V_(umax) and V_(dmax) of that decreased, which were significantly different from preoperative values(F=2.792, F=3.561, F=3.305, F=2.362, P0.05), respectively. And postoperative CCOS scores of these patients were higher than 11 points, and average score of them was 13 points, and the lowest score in them was 12 points, and the full score in them was 16 points, and no patient required a second surgery. Conclusion: The Cine PC-MRI technique can contribute to guide the surgical strategy in the diagnosis and treatment of Arnold-Chiari malformation type Ⅰ, and it can quantitatively and qualitatively analyze the hydromechanics of cerebrospinal fluid.
【CateGory Index】: R445.2;R742
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