Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Medical Recapitulate》 2006-01
Add to Favorite Get Latest Update

Role of Neutrophil Elastase in the Repair of Lung Tissue Injury

TAN Shan-zhong,LIU Cheng-hai.(Liver Disease Institute,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)  
Neutrophil elastase is one of the most predominant neutral proteinase of proteinases in neutrophilic lysosome,It is possible to hydrolyze peri-bronchial tissue,injury bronchial cilia and epithelial cells,degrade elastin,and destroy structure of pulmonary alveolus.The neutrophilic elastase plays a important role in acute lung injury,bronchiectasis,emphysema and pulmonary fibrosis.In this review,the actions and mechanism of neutrophil elastase in the repairing lung injury were summarized.
【Fund】: 上海市科学技术委员会重点基础研究项目(04JC140069);; 上海高校中医内科学E-研究院建设计划(E03008);; 上海市教育委员会重点学科建设部分资助
【CateGory Index】: R563
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 3 Hits
1 Xie Er-Fan,Yang Zong-Cheng,et al Burn Research Institute,Southwestern Hospital,Third Military Medical College, Chongqing;Effects of neutrophils and their released products on the pathogenesis of smoke inhalation injury[J];CHINESE JOURNAL OF PATHOPHYSIOLOGY;1995-01
2 JIE Zhijun 1,CAI Yingyun 2,YANG Wenlan 2,JIN Meiling 2,ZHU Wei 2,ZHU Cifang 3. 1Department of Pulmonology,Xinghua Hospital,Shanghai Second Medical University,Shanghai 200092;The effect of α_1-antitrypsin on elastase and surfactant in acute lung injury in rabbits[J];Chinese Critical Care Medicine;2001-12
3 TAN Shan zhong 1,TAN Chun yu 1,JIANG Jian 2,et al. 1 Institute of Liver Diseases,Shanghai University of TCM,(Shanghai,201203)China; 2.Shuguang Affiliated Hospital,Shanghai University of TCM,China;Expression of Pancreatic Elastase in Dimethylnitrosamin -nduced Liver Fibrosis in Rats[J];Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases;2005-01
Chinese Journal Full-text Database 10 Hits
1 WU Xue xiang,CHEN Jian ming,JIANG Yao guang,et al. (Thoracic and Cardiovascular Surgery Research Center,Institute of Surgery Research,Daping Hospital, Third Military Medical University,Chongqing 400042,China);A preliminary study about protective effect of aprotinin on lung damage after chest impact trauma in rabbits[J];Journal of Traumatic Surgery;2004-04
2 ZENG Xian-zhang GAO Wei CUI Xiao-guang Department of Anesthesiology,the second Affiliated Hospital,Harbin Medical University,Harbin 150086,China;The effects of hypercapnia on neutrophil function during acute lung injury[J];International Journal of Anesthesiology and Resuscitation;2007-04
3 Li Jianquan, Gou Daming, Yu Zhihao, etal. ICU of Guizhou Province People's Hosptial,Guiyang, 550002;The protective effect of Sivelestat sodium hydrate on Erythocytes during cardiopulmonary bypass[J];Guizhou Medical Journal;2006-05
4 MA Jian-ling~1,WEN Shao-hui~1,XI Ning~2,LU Yong~3,JI Kun~1,CHEN Meng-zhun~1,PANG Bao-sen~4, XIN Ping~4,HUANG Xiu-xia~4,SHI Li-qing~1 (1 Department of Respiratory Medicine,Dongfang Hospital of Beijing University of Chinese Medicine,Beijing 100078,China;2 Journal Center of Beijing University of Chinese Medicine,Beijing 100029,China; 3 Department of Respiratory Medicine,Beijing Chaoyang Hospital,Beijing 100043,China; 4 Beijing Institute of Respiratory Medicine,Beijing 100043,China);Effects of Eliminating Wind and Dispersing Lung Formula on HIS,LTB4 and NE in plasma of the guinea pigs with airway hypersensitivity[J];China Journal of Traditional Chinese Medicine and Pharmacy;2013-09
5 ZHOU Jian, SHAN You-an, QIN Wen-li, et al.(Research Institute of Surgery, Daping Hospital, The Third Military Medical University, Chongqing 400042, China);Effects of TNF-α on expression of CD14 and scavenger receptorof mouse alveolar macrophages[J];Basic Medical Sciences and Clinics;2004-03
6 WANG He mei,DING Ri gao,RUAN Jin xiu (Institute of Pharmacology and Toxicology,Academy of Military Medical Sciences,Beijing 100850,China);Progress of the study on effect mechanism of neutrophils in acute lung injury[J];Chinese Journal of Industrial Medicine;2002-06
7 ZHU Hui-bin,GAO Cong-rong,LIU Wei-ping,et al.Department of Thoracic Surgery,the Second People's Hospital of Hefei,Hefei 230011,Anhui,China;Effect of Ligustrazine on Plasma sICAM and PMNE during Cardiopulmonary Bypass[J];Chinese Journal of General Practice;2009-10
8 WU Qi-biao~1, SUN Zi-kai~2,CAO Shi-hong~2,WAN Yi-gang~3(1.First Clinical College,Nanjing University of Traditional Chinese Medicine,Nanjing,210029,China;2.Jiangsu Provincial Hospital of TCM,Nanjing 210029,China;3.Nanjing Gulou Hospital,Nanjing 210008,China);Effect of Zhikuoning Decoction on Neutrophil Elastase of Animal Model with Bronchiectasis[J];LiShiZhen Medicine and Materia Medica Research;2005-12
9 NIU Ruji ,L IU Huiguo ,FU Juan Departmentof Respiratory Medicine,Tongji H ospital,Tongji Medical College,H uazhong University of Science and Technol- ogy,Wuhan4 30 0 30;Effects of Shenmai and Aminophylline on Apoptosis of Small Airway Smooth Muscle Cells and the Expression of Relevant Genes in Rats with Emphysema[J];华中科技大学学报(外文版);2002-04
10 ZHANG Xin1,WANG Ding-ding,MU Jie (1 Affiliated Hospital of Medical College,Qingdao University,Qingdao 266003,P.R.China);Therapeutical effect and mechanism of Fei Tong oral liquid on the acute lung injury in rats[J];Shandong Medical Journal;2013-07
Chinese Journal Full-text Database 10 Hits
1 ZHANG Pin-jie,ZHU Li-xin,GENG Xiao-ping(Department of General Surgery,The First Affiliated Hospital of Ahhui Medical University,Hefei 230022,China);p38 mitogen activated protein kinase pathway and its inhibitor[J];Anhui Medical and Pharmaceutical Journal;2010-05
2 QI Xiang-qian YU Ming- kun. Department of Neurosurgery,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China;Inflammatory response and cerebral edema after cerebral trauma[J];Chinese Journal of Neuromedicine;2007-08
3 Zheng Huaien,Cheng Tianmin,Lin Yuan,Su Yongping,Gu Dequan,Yan Guohe,Liu Xianhua (Department of Radiation Medicine,Third Military Medical College,Chongqing,630038);A quantitative study of pulmonary bleeding after blast, burn and combined burn-blast injuries in rats[J];Acta Academiae Medicinae Militaris Tertiae;1993-04
4 ;Advance and clinical significance of several important signal transduction passages[J];Acta Academiae Medicinae Militaris Tertiae;2003-02
5 WEI Wei,ZHOU Ji-hong,XU Jian-hong,LIU Da-wei,LI Xiao-yan(Institute of Traffic Medicine,State Key Laboratory of Trauma,Bruns and Combined Injury,Institute of Surgery Research,Daping Hospital,Thrid Military Medicine University,Chongqing 400042,China);Changes of TNF-α and IL-8 in blood plasma after blast injury combined with hypoxia in rats[J];Acta Academiae Medicinae Militaris Tertiae;2007-23
6 Zheng Huaien;Chen Tianmin;Lin Yuan;Gu Dequan;Yan Guohe(Department of Radiation Medicine,Third Military Medical University,Chongqing,630038);The appearance of crystal bodies in pulmonary alveoli after blast and combined burn-blast injuries in rats[J];ACTA ACADEMIAE MEDICINAE MILITARIS TERTIAE;1995-02
7 Zheng Huaien, Cheng Tianmin, Lin Yuan, Gu Dequan, Yan Guohe (Department of Radiation Medicine, Third Military Medical University, Chongqing,630038);A study on the nature of crystals in pulmonary alveoli after blast and combined burn blast injuries in rats[J];ACTA ACADEMIAE MEDICINAE MILITARIS TERTIAE;1997-04
8 ( WU Xu, WANG Bao-jie, ZHANG Guo-hua, et al. Department of Forensic Pathology, Faculty of Forensic Medicine, China Medical University, Shen yang 110001,China);Animal model of graded impact brain injury in rats[J];Chinese Journal of Forensic Medicine;2005-01
9 YU Jian-yun1,3, LI Jun-xiang1, GUO Ze-yun2, ZHAO Xiao-lin1, ZHAO Xu-dong4 (1.Department of Forensic Medicine, Kunming Medical College, Kunming 650031,China;2.Department of histology and embryology, Kunming Medical College, Kunming 650031,China;3.Department of Trauma Brain Injury,Kunming Medical College, Kunming 650031,China;4. Department of psychiatry, Kunming Medical College, Kunming 650031,China);Coma Criterion and classification Standard of Mild and Moderate Traumatic Brain Injury in Rats[J];Journal of Forensic Medicine;2008-01
10 ;Progress in Study of TLR and Immune Reaction[J];International Journal of Pediatrics;2006-06
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 ZHANG Li wei 1,ZHAO Chun gui 1,WANG Jin dong 2,YANG Pin 1 (1.Institute of Molecular Science,Shanxi University,Taiyuan 030006,China; 2.Institute of Pharamaceutical Research,Taiyuan 030006,China);Inhibition of elastase by forsythiaside from fructus forsythiae[J];Chemical Research and Application;2002-02
2 JIANG Jian. (Department of Medicine, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200021);Elastase mRNA expression of hepatic cells[J];Chinese Journal of Clinical Hepatology;2002-06
3 ;肝纤维化的发生机制[J];World Chinese Journal of Digestology;2000-06
4 ;Current situation in studies of liver fibrosis[J];World Chinese Journal of Digestology;2000-11
5 Xie Er-Fan,Yang Zong-Cheng,et al Burn Research Institute,Southwestern Hospital,Third Military Medical College, Chongqing;Effects of neutrophils and their released products on the pathogenesis of smoke inhalation injury[J];CHINESE JOURNAL OF PATHOPHYSIOLOGY;1995-01
6 Li Changeheng, Yan Yizhao Sun Renyu (Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing 100730);Comparative Study on the Inhibitory Elastase Capacity of Fructus Forsythiae, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis and Ligustrazini[J];China Journal of Chinese Materia Medica;1990-09
7 JIANG Jian , SHU Qiang, LING Guanglie, et al. Department of Medicine, Shuguang Hospital, Shanghai 200021, China;The elastase mRNA expression of migrating medial smooth muscle cells after the damage of balloon angioplasty[J];Chinese Journal of Cardiology;2001-05
8 LU Lungen,ZENG Minde,LI Jiqiang,et al. (Shanghai Institute of Digestive Disease, Renji Hospital, Shanghai Second Medical University Shanghai 200001);Expression of elastin in experimentsl fatty liver and liver fibrosis[J];Chinese Hepatology;1999-03
9 JIE Zhijun,YANG Wenlan,CAI Yingyun,et al.Department of Pulmonology,Zhongshan Hospital,Shanghai Me dical University,Shanghai 200032;The role of proteaseantiprotease imbalance in acute lung injury induced by endotoxin in rabbits[J];CHINESE CRITICAL CARE MEDICINE;2000-01
10 ZHU Guangfa,NIU Shanfu,ZHANG Hongzhi,et al. 1Department of Respiratory Disease,Shanghai First People′s Hospital,Shanghai 200080;Determination of serum pulmonary surfactant protein A and its significance in patients with acute lung injury[J];CHINESE CRITICAL CARE MEDICINE;2000-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved