Relationship Between Genetic Polymorphism of N-acetyltransferase 2 and Genetic Susceptibility to Disease
OUYANG Xiao-chun,LIU Zhen-hua.(Department of Neurology,Zhujiang Hospital,Southern Medical University,Guangzhou 510280,China)
Pathogenesis of many diseases is connected with influence of environmental factors and individual genetic sensitivity to detoxification enzymes.Mutations of N-acetyltransferase 2 lead to decreased enzyme function.In this review,correlation between the polymorphic N-acetyltransferase-2 and Genetic susceptibility to cancer,Parkinson′disease and Alzheimer′s disease is summarized.
【CateGory Index】： R394