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《Medical Recapitulate》 2006-01
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Progress in the Research on Cell Therapy for Diabetes

LONG Ai-mei,LI Fu-rong,LI Lu.(Department of Endocrinolog,Shenzhen People′s Hospital,Shenzhen,Guangdong 518020,China)  
Islet transplantation is an effective method for diabetes.But extensive application of the transplatation are limited due to deficiency of donor islet cells.Stem cells have great potentialities of the continuous proliferation and differentiation,and thus,it is thought to be a valuable source for generation of islets in vitro.Embryonic stem cells and adult stem cells derived from pancreas,bone marrow,and liver can be induced and transdifferentiated toward pancreatic endocrine cells under certain conditions.Future studies have to the efficiency of transdifferentiation and produce better functional pancreatic endocrine cells.
【Fund】: 国家重大基础研究前期研究项目(2004CCA01500);; 广东省自然科学基金重点项目(037415)
【CateGory Index】: R587.1
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