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《Medical Recapitulate》 2006-01
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Progress in Study of Tumor Necrosis Factor and Anticytokine Therapy in Heart Failure

RONG Zi-ping~1,CHANG Zhong-fei~1,SONG Xin-wei~2.(1.Zhejiang College of Traditional Chinese Medicen,Hangzhou 310053,China;2.Zhejiang Hospital of Traditional Chinese Medicine,Hangzhou 310006,China)  
Heart failure is terminal phase of majority primary hear diseases.Increasing evidence suggests that cytokines,sush as tumor necrosis factor,may play a important role in the development of heart failure.It could induce or aggravate heart failure by inhibiting myocardial contractility,accelerating cardiac apotosis and reconstituting myocard.Anticytokine therapy have became a hot spot of heart failure because of the cognition of biological effect and mechanism of cytokines.In this review the action mechanism of the cytokines in the heart failure and present status of the anticytokine for heart failure is summarized.
【CateGory Index】: R541.6
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【Secondary References】
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